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Emanuela Pesce

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Ricercatore sanitario

Istituto Giannina Gaslini

Italy

Research Interests

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A drug repositioning approach for the discovery of LaminB1 regulators: towards a treatment for adult onset Autosomal Dominant LeukoDystrophy (ADLD)

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Articles (7)

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Collaborators (5)

Renata Bocciardi

Associate Professor

University of Genoa

ITALY

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Elvira Sondo

Istituto Giannina Gaslini

ITALY

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Carlo Castellani

Head of Cystic Fibrosis Center

Istituto Giannina Gaslini

ITALY

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Claudio Sorio

Associate professor

Università degli Studi della Campania Luigi Vanvitelli Scuola di Medicina e Chirurgia

ITALY

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Luis Galietta

Associate Professor

Università degli Studi di Napoli Federico II

ITALY

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Emanuela Pesce

Research Interests

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Recent Grants

Articles (7)

The apical mucus layer alters the pharmacological properties of the airway epithelium

Elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis and rare mutations

Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators

Deleterious effect of P. aeruginosa on F508del-CFTR rescued by Elexacaftor/Tezacaftor/Ivacaftor is clinical-strain dependent in patient-derived nasal cells

Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine

Rescue by elexacaftor-tezacaftor-ivacaftor of the G1244E cystic fibrosis mutation's stability and gating defects are dependent on cell background

Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators

Collaborators (5)

Renata Bocciardi

Elvira Sondo

Carlo Castellani

Claudio Sorio

Luis Galietta

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