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Emmanuel Donnadieu

Has grant

Head of unit

INSERM

France

Research Interests

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Recent Grants

Grant: Close

A novel 4D ex vivo human lymphoma model to assess CAR T and NK cell efficacy – 4D-CARLY

Open Date: 2023-01-04

Close Date: 2026-01-03

Grant: Close

NGTC - INSERM

Open Date: 2022-07-08

Close Date: 2025-05-31

Grant: Open

Next Generation T cell therapies for childhood cancers (NexTGen)

Open Date: 2022-06-01

Close Date: 2027-05-31

Grant: Close

A novel 4D ex vivo human lymphoma model to assess CAR T and NK cell efficacy

Open Date: 2022-01-01

Close Date:

Grant: Close

Analysis of a sphingosine kinase signalling pathway activated by FcepsilonRI in mast cells

Open Date: 1997-05-01

Close Date: 2000-04-30

Articles (20)

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2023

Collaborators (22)

Giovanni Tonon

Unit Head

Ospedale San Raffaele

ITALY

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Christian Buchholz

Paul-Ehrlich-Institut

GERMANY

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Anne Molitor

University of Strasbourg

FRANCE

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Federica Ungaro

Group Leader

Ospedale San Raffaele

ITALY

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Maik Luu

Professor Dr. rer. nat.

University Hospital Würzburg

GERMANY

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Maria Chiara BONINI

Professor

Università Vita Salute San Raffaele

ITALY

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Marie-Clotilde Alves-Guerra

Directeur de Recherche

Institut Cochin

FRANCE

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Laura Fouassier

Team leader and deputy director of NABI lab

Sorbonne Université

FRANCE

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Luca Simula

Permanent Researcher (CRCN INSERM)

Institut Cochin

FRANCE

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Alexandre Belot

Professeur de pédiatrie, enseignant chercheur-praticien hospitalier (PUPH)

Université Claude Bernard Lyon 1

FRANCE

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Julien Zuber

Professor of Clinical Immunology, PU-PH

Université Paris Descartes

FRANCE

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Andres Daniel Maturana

Nagoya University

JAPAN

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Nathalie Salome

senior scientist

INSERM

FRANCE

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Anne Galy

Director

INSERM

FRANCE

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Fabio Ciceri

Associate Professor of Hematology

Vita-Salute San Raffaele University

ITALY

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Biagio De Angelis

Dirigente Farmacista

Ospedale Pediatrico Bambino Gesù

ITALY

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Roland Hischier

Head "Advancing Life Cycle Assessment" Group

Empa

SWITZERLAND

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Cristina CASTILLA LLORENTE

Institut Gustave Roussy

FRANCE

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Lorena García-Hevia

Universidad de Cantabria

SPAIN

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Frederick Wilhelm Thielen

Senior researcher

Erasmus Universiteit Rotterdam Erasmus School of Health Policy and Management

NETHERLANDS

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Amanpreet Kaur

Associate Professor & Ramalingaswami Fellow

Amity University Noida

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Caroline Spenlé

Associate Professor

University of Strasbourg

FRANCE

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Emmanuel Donnadieu

Research Interests

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Recent Grants

Articles (20)

Laser-activated nanoparticles rewire tumor microenvironment enhancing PD-1 blockade and T cell response in cholangiocarcinoma

An in vivo CRISPR screen unveils promising target genes to improve CAR-T cell efficacy in a solid tumor model.

Call for preserving specialized knowledge and contributions of the CAT to advancing ATMPs in Europe

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Vers une production in vivo de cellules CAR-T

An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol.

Systemic Delivery of Cadherin 17-specific CAR-T Cells Allows Effective and Safe Targeting of Colorectal Cancer Liver Metastases

CAR T-cell therapy in autoimmune diseases: where are we and where are we going?

Degrading cancer cell mitochondria to improve T cell-mediated killing

Inhibition of Atg7 in intestinal epithelial cells drives resistance against Citrobacter rodentium

CAR-T cell therapy for juvenile-onset autoimmune diseases: a promising future?

A preclinical organotypic model for evaluating immunotherapy-related toxicities.

Precision-cut tumor tissue slices, a novel tool to study the tumor microenvironment interactions with chimeric antigen receptor (CAR) T cells.

Migration Dynamics of Human NK Cell Preparations in Microchannels and Their Invasion Into Patient-Derived Tissue.

Targeting the MAtrix REgulating MOtif abolishes several hallmarks of cancer, triggering antitumor immunity

Mitochondrial metabolism sustains CD8+ T cell migration for an efficient infiltration into solid tumors

Subverting Attachment to Prevent Attacking: Alteration of Effector Immune Cell Migration and Adhesion as a Key Mechanism of Tumor Immune Evasion

Checkpoint inhibition enhances cell contacts between CD4<sup>+</sup> T cells and Hodgkin-Reed-Sternberg cells of classic Hodgkin lymphoma.

Protocol for real-time monitoring of CD8&lt;sup&gt;+&lt;/sup&gt; T and myeloid cell behavior in human high-grade serous ovarian cancer slices.

ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma

Collaborators (22)

Giovanni Tonon

Christian Buchholz

Anne Molitor

Federica Ungaro

Maik Luu

Maria Chiara BONINI

Marie-Clotilde Alves-Guerra

Laura Fouassier

Luca Simula

Alexandre Belot

Julien Zuber

Andres Daniel Maturana

Nathalie Salome

Anne Galy

Fabio Ciceri

Biagio De Angelis

Roland Hischier

Cristina CASTILLA LLORENTE

Lorena García-Hevia

Frederick Wilhelm Thielen

Amanpreet Kaur

Caroline Spenlé

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Protocol for real-time monitoring of CD8<sup>+</sup> T and myeloid cell behavior in human high-grade serous ovarian cancer slices.