Erik Debler

Associate Professor

Thomas Jefferson University

United States

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Dr. Erik Debler is an Associate Professor at Thomas Jefferson University in the United States. His research focuses on chromatin remodeling, protein interactions with DNA, and the mechanisms of histone modification, as evidenced by his recent publications. He is particularly interested in the structural and functional dynamics of proteins involved in gene regulation and their implications for cellular processes.

Articles (6)

Year:

2024

Year:

2024

Year:

2023

Year:

2022

Year:

UNITED STATES

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Washington University in Saint Louis School of Medicine

UNITED STATES

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Erik Debler

Research Interests

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Articles (6)

The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS

Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids

Synthesis and characterization of I-BET151 derivatives for use in identifying protein targets in the African trypanosome

Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitment

Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates.

Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme)

Collaborators (9)

Gracyn Buenconsejo

M. Yusuf ALi

Chunyu Wang

Steven McMahon

Danae Schulz

Hideharu Hashimoto

Sozanne R Solmaz

Ramana Davuluri

Yixuan Xie

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