Estela Castilla-Ortega

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Profesora Contratada Doctora

University of Malaga

Spain

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Estela Castilla-Ortega is a Profesora Contratada Doctora at Universidad de Málaga, Spain. Her research focuses on neurogenesis, memory, and the effects of dietary components, particularly cocoa, on brain health. Recent articles cover areas such as metabolic profiles of cocoa powders, neurogenic effects of paracetamol, and the role of specific biomarkers in psychiatric conditions. She employs a multidisciplinary approach to explore the intersection of nutrition and neurobiology.

Recent Grants

Grant: Close

Estrategias nutricionales para potenciar la neurogénesis y la función hipocampal: uso de cacao como nuevo tratamiento para las alteraciones cognitivas inducidas por la cocaína

Open Date: 2021-09-01

Close Date: 2024-09-01

Grant: Close

Incremento de la neurogénesis hipocampal adulta como estrategia terapéutica para las alteraciones conductuales inducidas por cocaína

Open Date: 2016-12-01

Close Date: 2019-12-01

Grant: Close

Personal de Apoyo a la Investigación - Proyecto PSI2013-44901

Open Date: 2016-03-01

Close Date: 2016-12-01

Grant: Close

Interacción del consumo abusivo de alcohol y cannabis en neurogénesis durante la adolescencia: prevención del deterioro cognitivo

Open Date: 2016-01-01

Close Date: 2018-12-01

Grant: Close

Papel del Ácido Lisofosfatídico en el Alcoholismo y la Comorbilidad Psiquiátrica: Implicaciones Terapéuticas y Evaluación de Biomarcadores

Open Date: 2015-01-01

Close Date: 2017-01-01

Articles (16)

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2021

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2021

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2021

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2021

Collaborators (21)

Luis M Real

Profesor

Universidad de Sevilla

SPAIN

Estela Castilla-Ortega

Research Interests

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About

Recent Grants

Articles (16)

Correction: Plasma concentrations of lysophosphatidic acid and the expression of its receptors in peripheral blood mononuclear cells are altered in patients with cocaine use disorders

Inhibition of Adult Neurogenesis in Male Mice after Repeated Exposure to Paracetamol Overdose

Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory.

Integration of network-based approaches for assessing variations in metabolic profiles of alkalized and non-alkalized commercial cocoa powders.

How Healthy Is It to Fortify Cocoa-Based Products with Cocoa Flavanols? A Comprehensive Review

Exploring the Nutritional Composition and Bioactive Compounds in Different Cocoa Powders

A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease

Plasma concentrations of lysophosphatidic acid and the expression of its receptors in peripheral blood mononuclear cells are altered in patients with cocaine use disorders

miRNA-132/212 Deficiency Disrupts Selective Corticosterone Modulation of Dorsal vs. Ventral Hippocampal Metaplasticity

Environmental enrichment alleviates cognitive and psychomotor alterations and increases adult hippocampal neurogenesis in cocaine withdrawn mice

Plasma Lysophosphatidic Acid Concentrations in Sex Differences and Psychiatric Comorbidity in Patients with Cocaine Use Disorder

Sex-specific variations in spatial reference memory acquisition: Insights from a comprehensive behavioral test battery in C57BL/6JRj mice.

Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease

Persistent changes in exploration and hyperactivity coexist with cognitive impairment in mice withdrawn from chronic cocaine.

GABAergic deficits in absence of LPA<sub>1</sub> receptor, associated anxiety-like and coping behaviors, and amelioration by interneuron precursor transplants into the dorsal hippocampus.

Remote memory of drug experiences coexists with cognitive decline and abnormal adult neurogenesis in an animal model of cocaine‐altered cognition

Collaborators (21)

Luis M Real

Laura Sánchez Marín

PEDRO FERNANDO ARAOS GÓMEZ

Francisco Monje

Juan Manuel Decara Del Olmo

Ana Maria Brokate

Tarik Smani Hajami

María Inmaculada García Fernández

Elisa Matas-Rico

Xaver Koenig

David Ladrón de Guevara-Miranda

Guillermo Estivill-Torrús

Vito Verardo

María Flores López

Agustín Wallace Ruiz

Patricia Sampedro-Piquero

Fabiola Ávila Gámiz

Celia Rodriguez-Perez

Carmen Pedraza Benitez

Jose Luis Royo

Ernst Urban

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