Esther Sammler

United Kingdom

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Articles (21)

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2025

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Collaborators (21)

Courtney Thaxton

Assistant Professor

University of North Carolina at Chapel Hill

UNITED STATES

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Rui Moreira

Full Professor

Faculty of Pharmacy, University of Lisbon

PORTUGAL

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David J. Pedrosa

GERMANY

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K Ray Chaudhuri

King’s College London

UNITED KINGDOM

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Fritz Sedlazeck

Associate Professor

Baylor College of Medicine

UNITED STATES

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Alexander Zimprich

Principal Investigator/Associate Prof. Dr.

Medical University of Vienna

AUSTRIA

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Emily Forbes

University of Colorado Anschutz Medical Campus

UNITED STATES

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David Crosiers

Professor at University of Antwerp

University of Antwerp

BELGIUM

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Xingui Liu

Assistant Professor

University of Florida

UNITED STATES

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Stephen Mullin

University of Plymouth

UNITED KINGDOM

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Kelly Nudelman

Assistant Research Professor

Indiana University School of Medicine

UNITED STATES

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Teresa Ximelis Malondra

Fundació Institut d'Investigació Sanitària Illes Balears

SPAIN

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Daniel van Wamelen

King’s College London

UNITED KINGDOM

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Wim Mandemakers

Erasmus University Rotterdam

NETHERLANDS

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Deborah Mascalzoni

Uppsala University

SWEDEN

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Jia Nee Foo

Nanyang Assistant Professor

Nanyang Technological University (NTU)

SINGAPORE

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Christine Klein

GERMANY

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Agnita Boon

Erasmus University Rotterdam

NETHERLANDS

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Wilma van de Berg

Associate professor

Amsterdam UMC

NETHERLANDS

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Joanna Siuda

Medical University of Silesia

POLAND

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Mahima Swamy

Academic, Senior Lecturer (T and R) and Sir Henry Dale Fellow

University of Dundee

UNITED KINGDOM

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Esther Sammler

Research Interests

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Articles (21)

Treatment Selection and Prioritization for the EJS ACT-PD MAMS Trial Platform

Clinical and functional evidence for the pathogenicity of the LRRK2 p.Arg1067Gln variant

Inflammation and IL-4 regulate Parkinson’s and Crohn’s disease associated kinase LRRK2

PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson's disease

Functional and Structural Characterization of LRRK2 p.V1447L in Parkinson's Disease

Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples

Relevance of genetic testing in the gene-targeted trial era: the Rostock Parkinson's disease study.

Uncovering the genetic basis of Parkinson's disease globally

The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice

The protean presentations of XK disease (McLeod syndrome)

The New p.<scp>F1700L LRRK2</scp> Variant Causes Parkinson's Disease by Extensively Increasing Kinase Activity

Frequency of non-motor symptoms in Parkinson's disease patients carrying the E326K and T369M GBA risk variants

Comprehensive short and long read sequencing analysis for the Gaucher and Parkinson’s disease-associated GBA gene

Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

Impact of 100 LRRK2 variants linked to Parkinson’s disease on kinase activity and microtubule binding

Molecular mechanisms defining penetrance of LRRK2-associated Parkinson's disease

LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson’s disease and dementia with Lewy bodies

The commercial genetic testing landscape for Parkinson's disease.

Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites.

LIPAD (LRRK2/Luebeck International Parkinson's Disease) Study Protocol: Deep Phenotyping of an International Genetic Cohort.

R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils.

Collaborators (21)

Courtney Thaxton

Rui Moreira

David J. Pedrosa

K Ray Chaudhuri

Fritz Sedlazeck

Alexander Zimprich

Emily Forbes

David Crosiers

Xingui Liu

Stephen Mullin

Kelly Nudelman

Teresa Ximelis Malondra

Daniel van Wamelen

Wim Mandemakers

Deborah Mascalzoni

Jia Nee Foo

Christine Klein

Agnita Boon

Wilma van de Berg

Joanna Siuda

Mahima Swamy

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