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Eyal Gottlieb

Has grant

Professor

The University of Texas MD Anderson Cancer Center

United States

Research Interests

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Recent Grants

Grant: Close

Identifying metabolic drug targets that enhance response and overcome resistance to immune checkpoint blockade therapy in melanoma

Open Date: 2022-01-01

Close Date: 2024-12-01

Grant: Close

Uncovering Nutrient Vulnerabilities to stall Tumor Growth in vivo

Open Date: 2021-01-01

Close Date:

Grant: Close

Defining sensitivity and overcoming resistance to PARP inhibition in pancreatic ductal adenocarcinoma using combined genomics and metabolomics tools

Open Date: 2020-01-01

Close Date: 2023-12-31

Grant: Close

Discovering and exploiting the role of amino acids metabolism as safeguard mechanisms from ionizing radiation-induced redox stress and as novel targets for radiosensitization and immunosensitization therapies

Open Date: 2019-07-01

Close Date: 2022-06-01

Grant: Close

Genetic forms of peripartum heart failure: an iPSC-based approach to identify underlying pathomechanisms and development of corresponding preclinical mouse models

Open Date: 2019-05-09

Close Date:

Articles (20)

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Collaborators (19)

Moran Amit

The University of Texas MD Anderson Cancer Center

UNITED STATES

Eyal Gottlieb

Research Interests

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Recent Grants

Articles (20)

Psilocybin prevents chemotherapy-induced peripheral neuropathy via mitochondrial trafficking preservation

A step-by-step guide to performing cancer metabolism research using custom-made media

Selective Alanine Transporter Utilization is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer.

IFN-β production promotes metabolic rewiring and protection against oxidative stress in hepatitis delta virus-infected hepatocyte cultures.

EGFR controls transcriptional and metabolic rewiring in KRASG12D colorectal cancer

A metabolic switch to the pentose-phosphate pathway induces radiation resistance in pancreatic cancer

Metabolic consequences of altered kidney glucose reabsorption under normoglycemic conditions

Metabolic reprogramming driven by Ant2 deficiency augments T Cell function and anti-tumor immunity in mice

Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD

Programming a Ferroptosis‐to‐Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy

Metabolic alterations and cellular responses to β-Hydroxybutyrate treatment in breast cancer cells.

Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort

Failure to mate enhances investment in behaviors that may promote mating reward and impairs the ability to cope with stressors via a subpopulation of Neuropeptide F receptor neurons

Genetically engineering glycolysis in T cells increases their antitumor function

Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis

Knowledge-Based Therapeutics for Tricarboxylic Acid (TCA) Cycle-Deficient Cancers

Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells

Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction

Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production

Regulation of nucleo-cytosolic 26S proteasome translocation by aromatic amino acids via mTOR is essential for cell survival under stress

Collaborators (19)

Moran Amit

Sima Lev

Fabien Zoulim

Barbara Martinez Pastor

Patrick Dougherty

Birke Bartosch

Juliane Winkler

Lorenzo G. Cohen

Caroline Chidley

Dana Krauß

Yusuke Matoba

marie migaud

Arvand Haschemi

FREDERICO OMAR GLEBER NETTO

Dan Yaniv

Maria Sibilia

Aaron Goldman

DONGSHAN YANG

Erin Seeley

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