Fabio Di Domenico

Full Professor

Sapienza University of Rome

Italy

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Articles (10)

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (9)

Francesca Cutruzzola'

Full Professor of Molecular Biology

Università degli Studi di Roma La Sapienza

ITALY

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Federico Marini

Full professor

Università degli Studi di Roma La Sapienza

ITALY

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serena rinaldo

Associate Professor - Molecular Biology

Sapienza University of Rome

ITALY

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Eleonora Palma

Full Professor

Sapienza University of Rome

ITALY

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Claudio GRASSI

Università Cattolica del Sacro Cuore -Fondazione Policlinico Universitario Agostino Gemelli - IRCCS

ITALY

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Marzia Perluigi

ITALY

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Gabriele Ruffolo

Sapienza University of Rome

ITALY

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Eugenio Barone

Associate Professor

Sapienza University of Rome

ITALY

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Cristian RIPOLI

Associate Professor

ITALY

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Fabio Di Domenico

Research Interests

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Articles (10)

Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer’s Disease-Like Neuropathology in a Mouse Model for Down Syndrome

The disturbance of protein synthesis/degradation homeostasis is a common trait of age-related neurodegenerative disorders.

CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome.

Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles

High-fat diet leads to reduced protein o-glcnacylation and mitochondrial defects promoting the development of alzheimer’s disease signatures

The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease.

mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder.

Stress Responses in Down Syndrome Neurodegeneration: State of the Art and Therapeutic Molecules

The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome

Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: A harmful synergistic path in down syndrome.

Collaborators (9)

Francesca Cutruzzola'

Federico Marini

serena rinaldo

Eleonora Palma

Claudio GRASSI

Marzia Perluigi

Gabriele Ruffolo

Eugenio Barone

Cristian RIPOLI

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