Fernando Remião

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Professor

Universidade do Porto Faculdade de Medicina

Portugal

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About

Fernando Remião is a Professor at Universidade do Porto Faculdade de Farmacia in Portugal. His research areas include the effects of synthetic cannabinoids and cathinones on cellular and mitochondrial functions, as well as the application of metabolomics in understanding the impact of these substances. He has published extensively on topics such as neurotoxicity mechanisms and developmental effects of designer drugs, contributing valuable insights into pharmacology and toxicology.

Recent Grants

Grant: Close

INES: Innovative teaching and learning paths for the prevention of new drugs abuse

Open Date: 2021-12-01

Close Date: 2024-11-30

Grant: Close

SUCTIA - SYSTEMIC UNIVERSITY CHANGE TOWARDS INTERNATIONALISATION for Academia

Open Date: 2021-03-01

Close Date: 2023-08-01

Grant: Close

Pensos antimicrobianos e halocrómicos à base de fibras para o tratamento de feridas baseados em novas moléculas derivadas de pirimidina

Open Date: 2021-02-01

Close Date: 2024-01-01

Grant: Close

OEMONOM: Open access Educational Materials on Naturally Occurring Molecules - sources, biological activity and use

Open Date: 2019-09-01

Close Date: 2023-08-31

Grant: Close

Antimicrobials from the sea: models for innovative agents to revert multidrug resistance antimicrobial resistance in health and aquatic pollution

Open Date: 2018-01-01

Close Date: 2021-05-01

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Collaborators (18)

João Pedro Silva

University of Porto

PORTUGAL

Fernando Remião

Research Interests

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About

Recent Grants

Articles (28)

Exploring the Impact of Chirality of Synthetic Cannabinoids and Cathinones: A Systematic Review on Enantioresolution Methods and Enantioselectivity Studies

Binding Affinity of Synthetic Cannabinoids to Human Serum Albumin: Site Characterization and Interaction Insights

The role of mitochondrial dysfunction and calcium dysregulation in 2C-I and 25I-NBOMe-induced neurotoxicity

Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior

Metabolomics as a Tool for Unraveling the Impact of Enantioselectivity in Cellular Metabolism

Synthetic Cathinones Induce Developmental Arrest, Reduce Reproductive Capacity, and Shorten Lifespan in the C. elegans Model

Uncovering the Metabolic Footprint of New Psychoactive Substances by Metabolomics: A Systematic Review

More than tools: “video lecture capture” as a step towards pedagogic differentiation

Rescuing a Troubled Tolcapone with PEGylated PLGA Nanoparticles: Design, Characterization, and Hepatotoxicity Evaluation

Mechanistic Insights into the Neurotoxicity of 2,5-Dimethoxyphenethylamines (2C) and Corresponding N-(2-methoxybenzyl)phenethylamine (NBOMe) Drugs

Co-Culture Models: Key Players in In Vitro Neurotoxicity, Neurodegeneration and BBB Modeling Studies

Synergistic anti‐bacterial activity of imidazole‐based azo dyes with polyvinylpyrrolidone‐coated silver nanoparticles

Comparative In Vitro Study of the Cytotoxic Effects of Doxorubicin’s Main Metabolites on Cardiac AC16 Cells Versus the Parent Drug

The Role of Nrf2 and Inflammation on the Dissimilar Cardiotoxicity of Doxorubicin in Two-Time Points: a Cardio-Oncology In Vivo Study Through Time

Disclosing the Antifungal Mechanisms of the Cyclam Salt H4[H2(4-CF3PhCH2)2Cyclam]Cl4 against Candida albicans and Candida krusei

Cellular and Mitochondrial Toxicity of Tolcapone, Entacapone, and New Nitrocatechol Derivatives

Research Models to Study Ferroptosis’s Impact in Neurodegenerative Diseases

An In Vitro Evaluation of the Potential Neuroprotective Effects of Intranasal Lipid Nanoparticles Containing Astaxanthin Obtained from Different Sources: Comparative Studies

Halochromic Silk Fabric as a Reversible pH-Sensor Based on a Novel 2-Aminoimidazole Azo Dye

Synergistic Antimicrobial Activity of Silver Nanoparticles with an Emergent Class of Azoimidazoles

Autophagy (but not metabolism) is a key event in mitoxantrone-induced cytotoxicity in differentiated AC16 cardiac cells

Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their N-Benzylphenethylamine (NBOMe) Analogues

Molecular mechanisms of ferroptosis and their involvement in brain diseases

Semi-Preparative Separation, Absolute Configuration, Stereochemical Stability and Effects on Human Neuronal Cells of MDPV Enantiomers

Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks

Assessment of the Permeability of 3,4-Methylenedioxypyrovalerone (MDPV) across the Caco-2 Monolayer for Estimation of Intestinal Absorption and Enantioselectivity

Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels

The role of inflammation and antioxidant defenses in the cardiotoxicity of doxorubicin in elderly CD-1 male mice

Collaborators (18)

João Pedro Silva

Vera Marisa Costa

Fátima Cerqueira

José Teixeira

Daniel José Barbosa

Paulo Oliveira

Carla Fernandes

Andrea Zille

Ana I. Morales

Alice Dias

Eugénia Pinto

Renata Silva

Ana Catarina Silva

Carlos Fernandes

J. M. Sousa Lobo

Félix Carvalho

Patricio Soares-da-Silva

Emília Sousa

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