Paulo Oliveira

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Invited Assistant Professor

University of Coimbra

Portugal

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About

Paulo Oliveira is an Invited Assistant Professor at the University of Coimbra, Portugal. His research focuses on mitochondrial dysfunction, oxidative stress, and metabolic reprogramming, as evidenced by recent publications on the effects of methylphenidate and Equisetum ramosissimum. He also investigates the implications of mechanical cues on metabolic homeostasis and has contributed to understanding the antitumor mechanisms of natural compounds. His work is critical for addressing metabolic syndromes and enhancing therapeutic strategies in various cellular contexts.

Recent Grants

Grant: Close

Células Neuronais Humanas Diferenciadas a partir de Células Estaminais Derivadas de Urina como Plataforma para a Medicina Personalizada na Esclerose Lateral Amiotrófica

Open Date: 2022-01-15

Close Date: 2025-01-14

Grant: Close

Mitocôndria como potencial mediador do dimorfismo sexual nas alterações pato-morfológicas da microglia e ansiedade causadas pelo stress pré-natal<br>

Open Date: 2022-01-01

Close Date: 2023-06-30

Grant: Close

Função da homeostasia tiol-mitocondrial na neurodegeneração: implicações para a esclerose lateral amiotrófica

Open Date: 2022-01-01

Close Date: 2023-06-30

Grant: Close

Organelle-targeted Radiocomplexes for Auger Therapy of Cancer

Open Date: 2021-01-01

Close Date: 2023-12-31

Grant: Close

Preservação do património natural e cultural e validação científica das práticas com plantas medicinais do Vale do Côa

Open Date: 2020-07-01

Close Date: 2023-06-30

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Collaborators (34)

Filomena S. G. Silva

University of Coimbra

PORTUGAL

Paulo Oliveira

Research Interests

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About

Recent Grants

Articles (28)

Heterogeneous redox responses in NHDF cells primed to enhance mitochondrial bioenergetics

Mechanistic insights into Equisetum ramosissimum-mediated protection against palmitic acid-induced mitochondrial dysfunction and oxidative stress in a cell model for liver steatosis

Tackling overweight and obesity in the youth with the PAS GRAS project

Methylphenidate triggers retinal oxidative stress and mitochondrial dysfunction under physiological conditions but has beneficial effects in inflammatory settings

Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux

Adenine nucleotide translocase 2 silencing promotes metabolic reprogramming in P19 embryonal carcinoma stem cells

The (un)known crosstalk between metabolism and mechanotransduction: Implications for metabolic syndrome (MetS)-associated neurological complications

p66Shc signaling and autophagy impact on C2C12 myoblast differentiation during senescence

Age-dependent energy metabolism and transcriptome changes in urine-derived stem cells

Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN<sub>6</sub> sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism

Effect of Urolithin A on Bovine Sperm Capacitation and In Vitro Fertilization

Best practices for data management and sharing in experimental biomedical research

Real‐time OXPHOS capacity analysis in wounded skin from diabetic mice: A pilot study

Unveiling the antitumor mechanism of 7a-acetoxy-6ß-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma

Age-associated metabolic and epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes

Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity

Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing

Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models

Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks

Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress

TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status

Gestational Exercise Antagonises the Impact of Maternal High-Fat High-Sucrose Diet on Liver Mitochondrial Alterations and Quality Control Signalling in Male Offspring

The H9c2(2-1) cell-based sulforhodamine B assay is a non-animal alternative to evaluate municipal wastewater quality over time

Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions

Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model

Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease

Targeting Hydroxybenzoic Acids to Mitochondria as a Strategy to Delay Skin Ageing: An In Vitro Approach

Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations

Collaborators (34)

Filomena S. G. Silva

Filipa Ferreira

Fernando Remião

Paulo Santos

Ricardo Marques

Peter M. J. Quinn

Stephen H Tsang

Eduarda Pereira

Ludgero Tavares

Carlos Venâncio

Armando Caseiro

José Teixeira

Maria Paula Macedo

Yaiza Potes

Rosa Fernandes

Luis Antunes

Daniela Franco da Silva

Vilma A. Sardão

Paulo Matafome

Afshan Malik

Teresa Cunha-Oliveira

Fernanda Borges

Jorge Valero

Francisco B. Pereira

Celso Henrique Alves

Renata Silva

Nuno Raimundo

Gonçalo Afonso

Susana P. Pereira

Carlos Fernandes

Célia Cabral

Carla Varela

Miguel Ângelo Pardal

Ana Cristina Gonçalves

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