Flora Cheng

Macquarie University

Australia

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Articles (16)

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2025

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2025

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2025

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2024

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (31)

Carlo Russo

Macquarie University

AUSTRALIA

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Antonio Di Ieva

Macquarie University

AUSTRALIA

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Ian Blair

Macquarie University

AUSTRALIA

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Lívia Rosa Fernandes

Macquarie University

AUSTRALIA

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Sidong Liu

Macquarie University

AUSTRALIA

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Cyril Jones Jagaraj

Macquarie University

AUSTRALIA

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Angela Laird

Macquarie University

AUSTRALIA

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Julie Atkin

Macquarie University

AUSTRALIA

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Sarah Lyn Rea

Lab Head: Functional Genomics Group; Senior Research Fellow

Perron Institute for Neurological and Translational Science

AUSTRALIA

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Alison Hogan

Macquarie University

AUSTRALIA

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Natalie Grima

Macquarie University

AUSTRALIA

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Patrick A. Akkari

AUSTRALIA

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Jennifer Fifita

Macquarie University

AUSTRALIA

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Mark Molloy

Professor

University of Sydney

AUSTRALIA

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Stephanie Rayner

Macquarie University

AUSTRALIA

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Natalie Scherer

Macquarie University

AUSTRALIA

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Katherine Robinson

Macquarie University

AUSTRALIA

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Selina Zhang

Macquarie University

AUSTRALIA

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Maxinne Watchon

Macquarie University

AUSTRALIA

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Luan Luu

Macquarie University

AUSTRALIA

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Emily Don

Macquarie University

AUSTRALIA

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Hannah Suddull

Macquarie University

AUSTRALIA

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Shu Yang

Macquarie University

AUSTRALIA

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Marco Morsch

Macquarie University

AUSTRALIA

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Sharlynn Wu

Macquarie University

AUSTRALIA

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Sonia Sanz Muñoz

Københavns Universitet

DENMARK

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Jocelyn Widagdo

AUSTRALIA

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Rowan Radford

Macquarie University

AUSTRALIA

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Lezanne Ooi

University of Wollongong

AUSTRALIA

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Justin Yerbury

University of Wollongong

AUSTRALIA

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Albert Lee

Macquarie University

AUSTRALIA

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Flora Cheng

Research Interests

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Articles (16)

Proteomics analysis of the TDP-43 interactome in cellular models of ALS pathogenesis

FTO suppresses DNA repair by inhibiting PARP1

Cardio-metabolic and cytoskeletal proteomic signatures differentiate stress hypersensitivity in dystrophin-deficient mdx mice

Understanding age-related pathologic changes in TDP-43 functions and the consequence on RNA splicing and signalling in health and disease

Cyclin F can alter the turnover of TDP-43

Treatment with sodium butyrate induces autophagy resulting in therapeutic benefits for spinocerebellar ataxia type 3

The E3 ubiquitin ligase SCF cyclin F promotes sequestosome-1/p62 insolubility and foci formation and is dysregulated in ALS and FTD pathogenesis

Identification of phosphorylated tau protein interactors in progressive supranuclear palsy (PSP) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission

Inter-regional proteomic profiling of the human brain using an optimized protein extraction method from formalin-fixed tissue to identify signaling pathways

Cyclin F, Neurodegeneration, and the Pathogenesis of ALS/FTD

TDP-43 is a ubiquitylation substrate of the SCFcyclin F complex

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ

Unbiased label-free quantitative proteomics of cells expressing amyotrophic lateral sclerosis (ALS) mutations in CCNF reveals activation of the apoptosis pathway

p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death

Expanding the family of extracellular chaperones: Identification of human plasma proteins with chaperone activity

PeptideWitch–A Software Package to Produce High-Stringency Proteomics Data Visualizations from Label-Free Shotgun Proteomics Data

Collaborators (31)

Carlo Russo

Antonio Di Ieva

Ian Blair

Lívia Rosa Fernandes

Sidong Liu

Cyril Jones Jagaraj

Angela Laird

Julie Atkin

Sarah Lyn Rea

Alison Hogan

Natalie Grima

Patrick A. Akkari

Jennifer Fifita

Mark Molloy

Stephanie Rayner

Natalie Scherer

Katherine Robinson

Selina Zhang

Maxinne Watchon

Luan Luu

Emily Don

Hannah Suddull

Shu Yang

Marco Morsch

Sharlynn Wu

Sonia Sanz Muñoz

Jocelyn Widagdo

Rowan Radford

Lezanne Ooi

Justin Yerbury

Albert Lee

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