Florian Fröhlich

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Professor for Bioanalytical Chemistry

University of Osnabrück

Germany

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Florian Fröhlich is a Professor for Bioanalytical Chemistry at Osnabrück University in Germany. His research focuses on the mechanisms of lipid transport, lysosomal function in lipid homeostasis, and the structural dynamics of cellular complexes. Recent articles explore topics such as protein movement within cellular organelles and the role of specific kinases in cellular localization and function.

Recent Grants

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Mechanisms of ceramide sorting and transport between the endoplasmic reticulum and the Golgi apparatus in Saccharomyces cerevisiae

Open Date: 2021-01-01

Close Date: 2024-01-01

Grant: Close

Molecular dissection of sphingolipid and sterol homeostasis in yeast

Open Date: 2019-06-01

Close Date: 2022-06-01

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Mechanism of sphingolipid export from the endo-lysosomal system (P20*)

Open Date: 2019-01-01

Close Date:

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EvoCell

Open Date: 2018-10-01

Close Date: 2021-09-01

Grant: Close

Molecular dissection of sphingolipid and sterol homeostasis in yeast

Open Date: 2015-01-01

Close Date:

Articles (18)

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2025

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (20)

Claudio De Virgilio

Full Professor

University of Fribourg

SWITZERLAND

Florian Fröhlich

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About

Recent Grants

Articles (18)

Steric Repulsion Counteracts ER-to-Lipid Droplet Protein Movement

RpH-ILV: probe for lysosomal pH and acute LLOMe-induced membrane permeabilization in cell lines and Drosophila.

Structure of the endosomal CORVET tethering complex

Author Correction: Structure of the endosomal CORVET tethering complex.

Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuole

The role of lysosomes in lipid homeostasis

Yeast Svf1 binds ceramides and contributes to sphingolipid metabolism at the ER cis-Golgi interface

Structure of the ceramide-bound SPOTS complex

Identification of distinct active pools of yeast serine palmitoyltransferase in sub-compartments of the ER

Mechanisms of Nonvesicular Ceramide Transport

The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity

Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis

A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways

Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor

AP-3 vesicle uncoating occurs after HOPS-dependent vacuole tethering

Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex

The role of very long chain fatty acids in yeast physiology and human diseases

Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae

Collaborators (20)

Claudio De Virgilio

Elizabeth Miller

Muriel Mari

Lars Langemeyer

Inês Castro

Stefan Walter

Ayelén González Montoro

Raffaele Nicastro

Jan-Hannes Schäfer

Arne Moeller

Christian Ungermann

Oliver Schmidt

Laura Swan

Christer S. Ejsing

Ozren Stojanovic

Massimiliano Stagi

Emanuele Cocucci

Jacob Piehler

Robin Klemm

Margarita Cabrera

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