Franca Fraternali

Professor of Bioinformatics and Computational Biology

King’s College London

United Kingdom

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About

Franca Fraternali is a Professor of Bioinformatics and Computational Biology at King's College London, UK. Her research primarily focuses on antibody stability, the regulation of intestinal epithelial homeostasis, and the analysis of immune responses in autoimmune conditions. Recent publications include studies on IL36RN mutations, allosteric regulation of enzyme activity, and profiling protein interactions in the context of various diseases.

Articles (14)

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2025

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (28)

Maria A. Tossounian

University College London

UNITED KINGDOM

Franca Fraternali

Research Interests

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Articles (14)

Tuning antibody stability and function by rational designs of framework mutations

Walking with giants

TNIK: A redox sensor in endothelial cell permeability

IFN-γ-dependent regulation of intestinal epithelial homeostasis by NKT cells

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

In Silico and In Vitro Analysis of IL36RN Alterations Reveals Critical Residues for the Function of the Interleukin-36 Receptor Complex

PDBe-KB: collaboratively defining the biological context of structural data

Allosteric Regulation of the Soluble Epoxide Hydrolase by Nitro Fatty Acids

Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus

Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling

Profiling the Site of Protein CoAlation and Coenzyme A Stabilization Interactions

Pandemic, Epidemic, Endemic

Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation

Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer

Collaborators (28)

Maria A. Tossounian

Panagiotis Karagiannis

Steven Lynham

Stuart John Bevan

Alicia Michelle Chenoweth

Pathmanaban Ramasamy

Aleksandar Ivetic

Paweł Rubach

Petr Škoda

Saraid McIlvride

Giancarlo Abis

Nathalie Reuter

Mosharraf Sarker

Katherine Longman

Christian Margreitter

Francesca Capon

Jitesh Chauhan

Antonio Rosato

Simon Cleary

Gavin Bewick

Sophia Karagiannis

Diego Esposito

James Spicer

Deborah Dunn-Walters

Davide Danovi

Peter Jones

Jose Maria Carazo Garcia

Karel Berka

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