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Francesco Benedetti

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Professore II fascia SSD MED/25 - Psichiatria

Università Vita Salute San Raffaele

Italy

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Professors in Italy

About

Francesco Benedetti is a Professore II fascia SSD MED/25 - Psichiatria at Università Vita Salute San Raffaele in Italy. His research primarily focuses on the psychiatric effects of COVID-19, treatment-resistant depression, and the interplay of inflammation in psychopharmacology. His recent publications include studies on survivor guilt, cognitive functioning after COVID-19, and the mental health outcomes of COVID-19 survivors.

Recent Grants

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Inflammation and depression: a multidisciplinary approach to dissect pathogenetic mechanisms in the onset, comorbidity and treatment response.

Open Date: 2022-01-01

Close Date:

Grant: Close

HappyMums: Understanding, predicting, and treating depression in pregnancy to improve mothers and offspring mental health outcomes

Open Date: 2022-01-01

Close Date:

Grant: Close

Immune/inflammatory biomarkers in postpartum depression: pathogenetic mechanisms, MRI endophenotypes, and predictive biomarkers (PPDINFLAME)

Open Date: 2020-01-01

Close Date:

Grant: Close

Neuroinflammation in major depressive disorder with anxious distress: a precision medicine approach based on human cell biology, imaging genetics, and biomarkers of inflammation (NEUROINFLAME)

Open Date: 2019-01-01

Close Date:

Grant: Close

MOODSTRATIFICATION: Immune Signatures for Therapy Stratification in Major Mood Disorders

Open Date: 2018-01-01

Close Date: 2022-06-01

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Collaborators (35)

Peng Li

Assistant Investigator

Harvard Medical School

UNITED STATES

Francesco Benedetti

Research Interests

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About

Recent Grants

Articles (30)

Decomposing neuroanatomical heterogeneity in depression

Altered frontal and occipital cortical microstructure in obsessive-compulsive disorder - a multisite mega-analysis

Cumulative depressive burden, functional impairment, depressive symptomatology and treatment response in Major Depressive Disorder

Brain Morphology Mediators of the Association of Childhood Trauma with Bipolar Disorder: An International ENIGMA Bipolar Disorder Working Group Study

Family History and Solar Insolation in Bipolar I Disorder

Classification of major depressive disorder using vertex-wise brain sulcal depth, curvature, and thickness with a deep and a shallow learning model

Cortical morphometry might predict currently prescribed vs. discontinued medications in bipolar disorder, even after controlling for the cumulative dose effects: An ENIGMA mega-analysis

Fractal dynamics in spontaneous motor activity associate with effective antidepressant chronotherapeutic response, cerebellar volumes, and white matter microstructure in bipolar disorder

A Delphi-method-based consensus for clinical domains and assessment of the inflammatory subtype of major depressive disorder from the ASPIRE study

Exploring the Influence of Inflammation on the Pharmacokinetics of Antidepressants and Antipsychotics: A Systematic Review

Anti-inflammatories for depression: challenges and ASPIRations

Different effect of adverse childhood experiences on white matter microstructure in major depression and bipolar disorder: moderating role of genetic liability

Distribution and age-interactions of cortical thickness associated with specific classes of medication used to treat obsessive-compulsive disorder: Results from the international ENIGMA Consortium

CLOCK 3111T/C Polymorphism and Sex Moderate the Effect of Childhood Trauma on White Matter Microstructure in Bipolar Disorder

A European platform trial for major depressive disorder

Biotypes of deeply phenotyped depressed patients reflect signatures of adverse childhood experience and depressive cognitive biases

Brain signatures of childhood trauma and polygenic scores for mental health drive clinical subtypes in depression: a UK Biobank study

Chronotherapy shortens hospitalization for bipolar depression: a single-center replication across three decades (1994-2024)

Effects of total sleep deprivation and light therapy on resting-state activity and neurovascular coupling in bipolar depression

Executive Function in Obsessive-Compulsive Disorder: A Worldwide Mega-Analysis of Task-Based Functional Neuroimaging Data of the ENIGMA-OCD Consortium

The Burden of Survivorship: Survivor Guilt and Its Association with Psychiatric Sequelae in COVID-19 Patients

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials

Antidepressant psychopharmacology: is inflammation a future target?

Comment on: "Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current Evidence"

Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals

Long-term consequences of COVID-19 on cognitive functioning up to 6 months after discharge: role of depression and impact on quality of life

One-year mental health outcomes in a cohort of COVID-19 survivors

Rapid response to selective serotonin reuptake inhibitors in post-COVID depression

Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression

The self and its internal thought: In search for a psychological baseline

Collaborators (35)

Peng Li

Yann Quidé

Sarah Whittle

Roberto Goya‐Maldonado

Zeynep Başgöze

Guillermo Perez Algorta

Golam Khandaker

René E. Nielsen

Eric Achtyes

Yoshinari Abe

Mirko Manchia

David Mataix-Cols

Valeria Mondelli

Panagiotis Ferentinos

Thomas Pollak

Christopher Ching

Luisa Lazaro

Jan Ernsting

Marco Paolini

Dan Rujescu

Cynthia Fu

Fiona Juliet Rosalind Eccles

Javier Caso

Georgios Schoretsanitis

Violette Coppens

Danai Dima

Jamie Feusner

Michael Berk

Thomas Lancaster

Josselin Houenou

Klaus Martiny

Gloria Roberts

Jochen Bauer

Jose de Leon

Sara Poletti

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