Francis Ntumngia

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Associate Professor

University of South Florida

United States

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About

Francis Ntumngia is an Associate Professor at the University of South Florida, USA. His research focuses on various aspects of Plasmodium vivax and its interactions with the immune system, including the characterization of antibody responses and vaccine candidates. Recent articles highlight his work on naturally acquired antibodies, genetic diversity in Plasmodium vivax, and the effects of co-infections on immune responses.

Recent Grants

Grant: Close

Plasmodium vivax invasion of Duffy-negative reticulocytes: The missing link

Open Date: 2019-01-01

Close Date: 2019-12-01

Grant: Close

Defining epitopes of Plasmodium vivax Reticulocyte Binding Protein that are potential vaccine targets

Open Date: 2014-08-01

Close Date: 2017-11-01

Grant: Close

Immunological characterization of the P. vivax DBP

Open Date: 2005-04-01

Close Date: 2019-01-01

Articles (14)

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (2)

Jaap Michiel Middeldorp

Emeritus Prof.

Amsterdam UMC Locatie VUmc

NETHERLANDS

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John H. Adams

Distinguished University Professor

University of South Florida

UNITED STATES

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Francis Ntumngia

Research Interests

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About

Recent Grants

Articles (14)

Naturally acquired antibodies against Plasmodium vivax pre-erythrocytic stage vaccine antigens inhibit sporozoite invasion of human hepatocytes in vitro

Characterization of Duffy Binding Protein II-specific CD4 <sup>+</sup>T cell responses in Plasmodium vivax patients

Genetic diversity and natural selection of Plasmodium vivax reticulocyte invasion genes in Ecuador

Comparative analyses of functional antibody-mediated inhibition with anti-circumsporozoite monoclonal antibodies against transgenic Plasmodium berghei

IgM antibody responses against Plasmodium antigens in neotropical primates in the Brazilian Atlantic Forest

Preliminary characterization of Plasmodium vivax sporozoite antigens as pre-erythrocytic vaccine candidates

Antibody response to a new member of the DBL family (EBP2) after a brief Plasmodium vivax exposure

Impact of Epstein-Barr virus co-infection on natural acquired Plasmodium vivax antibody response

Cross-reactive inhibitory antibody and memory B cell responses to variant strains of Duffy binding protein II at post-Plasmodium vivax infection

The presence of circulating antibody secreting cells and long-lived memory B cell responses to reticulocyte binding protein 1a in Plasmodium vivax patients

Multiplexed Microsphere-Based Flow Cytometric Assay to Assess Strain Transcending Antibodies to Plasmodium vivax Duffy Binding Protein II Reveals an Efficient Tool to Identify Binding-Inhibitory Antibody Responders

Profiling Humoral Immune Response Against Pre-Erythrocytic and Erythrocytic Antigens of Malaria Parasites Among Neotropical Primates in the Brazilian Atlantic Forest

Variable immunogenicity of a vivax malaria blood-stage vaccine candidate

Dynamics of IgM and IgG responses to the next generation of engineered Duffy binding protein II immunogen: Strain-specific and strain-transcending immune responses over a nine-year period

Collaborators (2)

Jaap Michiel Middeldorp

John H. Adams

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