Frank Edenhofer

Prof., Head Dpt. Genomics, Stem Cell Biology & Regenerative Medicine

University of Innsbruck

Austria

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About

Professor Frank Edenhofer is the Head of the Department of Genomics, Stem Cell Biology & Regenerative Medicine at Universität Innsbruck, Austria. His research focuses on stem cell biology, regenerative medicine, and the genetic underpinnings of neurodegenerative diseases, as evidenced by his recent publications involving the generation of induced pluripotent stem cell lines and their application in studying conditions such as Alzheimer’s disease and Parkinson's disease. He is actively contributing to advancements in understanding neuronal development and dysfunction through innovative in vitro models.

Articles (12)

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2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (18)

Michaela Defrancesco

Medical University of Innsbruck

AUSTRIA

Frank Edenhofer

Research Interests

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About

Articles (12)

Single-cell Profiling of Reprogrammed Human Neural Stem Cells Unveils High Similarity to Neural Progenitors in the Developing Central Nervous System

Generation of the human induced pluripotent stem cell line (IBKMOLi003-A) from PBMCs of a vascular Ehlers-Danlos syndrome (vEDS) patient carrying the heterozygous nonsense mutation c.430C > T (p.Q105*) in the COL3A1 gene

The promise of genetic screens in human in vitro brain models

Emerging Role of miR-21-5p in Neuron-Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer's Disease

Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene

Targeting α-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models

Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients.

Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet.

CRISPR/Cas9-edited PKP2 knock-out (JMUi001-A-2) and DSG2 knock-out (JMUi001-A-3) iPSC lines as an isogenic human model system for arrhythmogenic cardiomyopathy (ACM).

Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting.

Autophagy in α-Synucleinopathies—An Overstrained System

High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts

Collaborators (18)

Michaela Defrancesco

Katharina Günther

Christopher Esk

Adelaide Fernandes

Dora Brites

Francesca Finotello

Jari Koistinaho

Dirk Meyer

Maria Cavinato

Frank Reimann

Jerome Mertens

Shauna Yuan

Larissa Traxler

Ana Rita Vaz

Pidder Jansen‐Duerr

Markus Hartl

Johannes Schlachetzki

Marta Suarez Cubero

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