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Franziska Denk

King’s College London

United Kingdom

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Research Interests

Systems Neuroscience

100%

Computational Neuroscience

50%

Inflammatory Biology

50%

Neuroscience

50%

Neuropathic Pain

30%

Neuroinflammation

30%

Clinical Neurophysiology

30%

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Recent Grants

Grant: Close

Latent enhancers - a novel mechanism for pain chronification?

Open Date: 2017-08-31

Close Date: 2020-08-30

Grant: Close

Functional significance of haplotype-specific variations in MAPT and their potential role in the pathogenesis of neurodegenerative disease.

Open Date: 2005-10-01

Close Date: 2008-09-30

Grant: Close

Functional significance of haplotype-specific variations in MAPT and their potential role in the pathogenesis of neurodegenerative disease.

Open Date: 2004-10-01

Close Date: 2008-09-30

Grant: Close

NGN-PET - Modelling Neuron-Glia Networks into a drug discovery platform for Pain Efficacious Treatments

Open Date:

Close Date:

Articles26

A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain?

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Year:

2025

Modelling inflammation-induced peripheral sensitization in a dish-more complex than expected?

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Year:

2025

Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons

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Year:

2025

Reply to Zhang and Jiao

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Year:

2025

Reply to Zhao et al

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Year:

2025

Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis

Article Link

Year:

2025

In vivo calcium imaging shows that satellite glial cells have increased activity in painful states

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Year:

2024

A randomised controlled trial of the effect of intra-articular lidocaine on pain scores in inflammatory arthritis

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Year:

2024

Deep sequencing of Phox2a nuclei reveals five classes of anterolateral system neurons

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Year:

2024

Assessing spontaneous sensory neuron activity using in vivo calcium imaging

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Year:

2024

Spontaneous activity in peripheral sensory nerves

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Year:

2024

Practical approaches to improving translatability and reproducibility in preclinical pain research

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Year:

2024

The local molecular signature of human peripheral neuropathic pain.

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Year:

2024

Harmonizing neuropathic pain research: outcomes of the London consensus meeting on peripheral tissue studies.

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Year:

2024

Modeling neuropathic pain in a dish.

Article Link

Year:

2024

Cerebrospinal fluid immune cells appear similar across neuropathic and non-neuropathic pain conditions

Article Link

Year:

2023

Comparative transcriptional analysis of satellite glial cell injury response

Article Link

Year:

2022

Early life inflammation is associated with spinal cord excitability and nociceptive sensitivity in human infants

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Year:

2022

Fibroblasts

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Year:

2022

Remembering Stephen McMahon, a great electrophysiologist, innovator and mentor

Article Link

Year:

2021

Examination of the contribution of Nav1.7 to axonal propagation in nociceptors

Article Link

Year:

2021

Probing the peripheral immune response in mouse models of oxaliplatin-induced peripheral neuropathy highlights their limited translatability

Article Link

Year:

2021

Changes in the transcriptional fingerprint of satellite glial cells following peripheral nerve injury

Article Link

Year:

2020

A transcriptional toolbox for exploring peripheral neuro-immune interactions

Article Link

Year:

2020

Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α-activated fibroblast-like synoviocytes: an in vitro, coculture model of inflammatory pain.

Article Link

Year:

2020

The impact of bone cancer on the peripheral encoding of mechanical pressure stimuli

Article Link

Year:

2020

Collaborators20

Maria M. Cobo

UNITED KINGDOM

Rebeccah Slater

Professor of Paediatric Neuroimaging

University of Oxford

UNITED KINGDOM

Marianne van der Vaart

University of Oxford

UNITED KINGDOM

Leonie Taams

King’s College London

UNITED KINGDOM

Caroline Hartley

University of Oxford

UNITED KINGDOM

Laura Fedele

King’s College London

UNITED KINGDOM

Sara Villa Hernandez

King’s College London

UNITED KINGDOM

Artur Kania

Institut de recherches cliniques de Montréal

CANADA

George Goodwin

King's College London

UNITED KINGDOM

Yuening Li

King's College London

UNITED KINGDOM

Eleonora Galosi

ITALY

Mateusz Kucharczyk

King’s College London

UNITED KINGDOM

Christian Bjerggaard Vægter

Aarhus University

DENMARK

Andrew Cooper

University of Glasgow

UNITED KINGDOM

Susan John

King’s College London

UNITED KINGDOM

Lone Tjener Pallesen

Associate Professor

Aarhus University

DENMARK

Andrew Bell

University of Glasgow

UNITED KINGDOM

Sam Norton

Prof at King's College London

King’s College London

UNITED KINGDOM

Sara E. Jager

Københavns Universitet

DENMARK

Zoe Lee Hore

King’s College London

UNITED KINGDOM

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