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Leonie Taams

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King’s College London

United Kingdom

Research Interests

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Recent Grants

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Determining the molecular mechanisms underlying IL-10 expression in human CD4+ T-cells following TNF blockade

Open Date: 2016-04-01

Close Date: 2021-03-01

Grant: Close

Identifying the molecular basis for regulatory T cell-induced anti-inflammatory functions of monocytes and macrophages

Open Date: 2014-10-01

Close Date: 2018-09-01

Grant: Close

Regulatory roles of JMJD3 domain and bromodomain-containing proteins in immunity and inflammation

Open Date: 2013-10-01

Close Date: 2017-09-01

Grant: Close

Experimental arthritis treatment centre

Open Date: 2012-07-01

Close Date: 2018-06-01

Grant: Close

Do activated monocytes impair regulatory T cell function in rheumatoid arthritis?

Open Date: 2010-11-01

Close Date: 2013-10-31

Articles (30)

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Collaborators (35)

Joseph J. Sacco

Clinical Senior Lecturer

University of Liverpool

UNITED KINGDOM

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Mario Falchi

Reader in Computational Medicine

King’s College London

UNITED KINGDOM

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Jorg van Loosdregt

University Medical Center Groningen

NETHERLANDS

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Bruce Kirkham

Professor of Translational Rheumatology

King’s College London

UNITED KINGDOM

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Soyon Hong

UNITED KINGDOM

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Sophie Papa

King’s College London

UNITED KINGDOM

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Henry Rogers

King’s College London

UNITED KINGDOM

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Mark Baker

Head of Department

Newcastle upon Tyne Hospitals NHS Foundation Trust

UNITED KINGDOM

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Laura Fedele

King’s College London

UNITED KINGDOM

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Marca Wauben

Professor Intercellular Communication

Utrecht University

NETHERLANDS

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Sara Villa Hernandez

King’s College London

UNITED KINGDOM

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Rocio Teresa Martinez-Nunez

King’s College London

UNITED KINGDOM

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Yuening Li

King's College London

UNITED KINGDOM

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Marc-Emmanuel Dumas

Principal Investigator and Group Leader

CNRS Délégation Nord Pas-de-Calais et Picardie

FRANCE

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Alasdair Coles

University of Cambridge

UNITED KINGDOM

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Rhys Thomas

Reader in Epilepsy

Newcastle University Faculty of Medical Sciences

UNITED KINGDOM

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Rachael Cooper

Trial Statistician

University of Liverpool

UNITED KINGDOM

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Ashley Jones

Head of Statistics

University of Liverpool

UNITED KINGDOM

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Panteleimon Takis

Assistant Professor

University of Ioannina

GREECE

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Aridaman Pandit

Assistant Professor

University Medical Center Groningen

NETHERLANDS

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David Bennett

University of Oxford

UNITED KINGDOM

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Franziska Denk

King’s College London

UNITED KINGDOM

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Nathalie Kingston

Research Professor

University of Cambridge

UNITED KINGDOM

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Leendert Trouw

Professor

Leiden University Medical Center

NETHERLANDS

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Susan John

King’s College London

UNITED KINGDOM

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Mandy Wan

King’s College London

UNITED KINGDOM

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Sam Norton

Prof at King's College London

King’s College London

UNITED KINGDOM

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Alexander Ren

Stanford University

UNITED STATES

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Tracey Sach

Professor in Health Economics

University of Southampton

UNITED KINGDOM

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Neil Harrison

Clinical Professor Neuroimaging

Cardiff University

UNITED KINGDOM

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Romit Samanta

NIHR Clinical Lecturer in Intensive Care Medicine

University of Cambridge

UNITED KINGDOM

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Richard Digby

NIHR Clinical Lecturer in Diagnostic Neuropathology

University of Leeds

UNITED KINGDOM

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kirsty bannister

Lecturer

King’s College London

UNITED KINGDOM

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Paul Lorigan

The University of Manchester

UNITED KINGDOM

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Domenico Somma

Honorary Lecturer

University of Glasgow

UNITED KINGDOM

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Leonie Taams

Research Interests

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Recent Grants

Articles (30)

Assessment of pain types in recently diagnosed patients with Inflammatory Arthritis

A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain?

Methotrexate and ciclosporin both reduce levels of circulating interleukin (IL)-4 and IL-13 expressing CD4+ memory T cells in childhood atopic dermatitis

Modelling inflammation-induced peripheral sensitization in a dish-more complex than expected?

Clonal sharing of CD8+ T-cells links skin and joint inflammation in psoriatic arthritis

Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons

Reply to Zhang and Jiao

My highlights as Editor-in-Chief of Clinical & Experimental Immunology, 2017–2024

Reply to Zhao et al

Lipidome profiling of neutrophil-derived extracellular vesicles unveils their contribution to the ensemble of synovial fluid-derived extracellular vesicles during joint inflammation

An interdisciplinary perspective on peripheral drivers of pain in rheumatoid arthritis

Substantive Similarities Between Synovial Fluid and Synovial Tissue T cells in Inflammatory Arthritis Via Single‐Cell RNA and T cell Receptor Sequencing

Clinical and Experimental Immunology: Highlights of 2023

BiTE therapy for rheumatoid arthritis

Comparative analysis of centrally mediated and inflammatory pain experiences amongst patients diagnosed with rheumatoid arthritis

Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells

A randomised controlled trial of the effect of intra-articular lidocaine on pain scores in inflammatory arthritis

Human in vitro-induced IL-17A+ CD8+ T-cells exert pro-inflammatory effects on synovial fibroblasts

Clinical and Experimental Immunology: highlights from 2022

Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial.

Type 17-specific immune pathways are active in early spondyloarthritis

Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses

Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma

Clinical & Experimental Immunology: Highlights of 2021

Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation

miR-155 overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T cell activation

55 years in the life of Clinical & Experimental Immunology

Research priorities for neuroimmunology

Drivers of Inflammation in Psoriatic Arthritis

Collaborators (35)

Joseph J. Sacco

Mario Falchi

Jorg van Loosdregt

Bruce Kirkham

Soyon Hong

Sophie Papa

Henry Rogers

Mark Baker

Laura Fedele

Marca Wauben

Sara Villa Hernandez

Rocio Teresa Martinez-Nunez

Yuening Li

Marc-Emmanuel Dumas

Alasdair Coles

Rhys Thomas

Rachael Cooper

Ashley Jones

Panteleimon Takis

Aridaman Pandit

David Bennett

Franziska Denk

Nathalie Kingston

Leendert Trouw

Susan John

Mandy Wan

Sam Norton

Alexander Ren

Tracey Sach

Neil Harrison

Romit Samanta

Richard Digby

kirsty bannister

Paul Lorigan

Domenico Somma

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