G. Sutherland

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University of Sydney

Australia

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NOVEL MECHANISMS UNDERLYING THE SPREADING OF TAU PATHOLOGY IN ALZHEIMERâ S DISEASE AND OTHER TAUOPATHIES

Open Date: 2012-01-01

Close Date: 2015-12-31

Grant: Close

Brain Tissue Resource Center for Alcohol Research

Open Date: 2000-09-01

Close Date: 2023-05-31

Articles (23)

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Collaborators (15)

Julia Stevens

University of Sydney

AUSTRALIA

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Consuelo Walss‐Bass

UNITED STATES

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Mark Larance

Senior Lecturer

University of Sydney

AUSTRALIA

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Asipu Sivaprasadarao

Emeritus Professor

University of Leeds

UNITED KINGDOM

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Caine Smith

University of Sydney

AUSTRALIA

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Paul Austin

Senior Lecturer in Neuroscience and Neuroanatomy

University of Sydney

AUSTRALIA

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Andrew Tsatsanis

St Vincent's Institute of Medical Research

AUSTRALIA

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Kerstin Lenk

Assistant Professor

Graz University of Technology

AUSTRIA

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Ellis Patrick

Associate Professor

University of Sydney

AUSTRALIA

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Joerg Eberhard

AUSTRALIA

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Eloise Kok

University of Tampere

FINLAND

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James Conigrave

Australian Catholic University - North Sydney Campus

AUSTRALIA

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Lezanne Ooi

University of Wollongong

AUSTRALIA

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Christine L Paul

AUSTRALIA

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Anthony S. Don

AUSTRALIA

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G. Sutherland

Research Interests

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Recent Grants

Articles (23)

Quantification of Alzheimer disease neuropathology using tissue microarrays

Loss of lysosomal acid lipase contributes to Alzheimer's disease pathology and cognitive decline.

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK Biobank.

Presenilin 1 hemizygosity has no overt deleterious phenotypic outcomes in sheep: Potential implications for therapeutic targets in Alzheimer's disease.

Integrative genomics approach identifies glial transcriptomic dysregulation and risk in the cortex of individuals with Alcohol Use Disorder.

The Experts Speak: Challenges in Banking Brain Tissue for Research

A systematic review and meta-analysis on the transcriptomic signatures in alcohol use disorder

Phosphatidylethanol in post-mortem brain: Correlation with blood alcohol concentration and alcohol use disorder

Increased Neuronal Nitric Oxide Synthase in Alzheimer's Disease Mediates Spontaneous Calcium Signaling and Divergent Glutamatergic Calcium Responses.

A Survey of Community Perceptions on Brain Donation for Research

Biological aging markers in blood and brain tissue indicate age acceleration in alcohol use disorder.

Double Chromogen-based Immunohistochemical Staining: An Efficient Approach for Utilizing Long-term Formalin-fixed Tissue in Biobanks

Ranking the risk factors for Alzheimer's disease; findings from the UK Biobank study.

Spatial analysis for highly multiplexed imaging data to identify tissue microenvironments

Central markers of neuroinflammation in alcohol use disorder: A meta‐analysis of neuroimaging, cerebral spinal fluid, and postmortem studies

Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.

The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus

Lipidome changes in alcohol‐related brain damage

Overlap between Central and Peripheral Transcriptomes in Parkinson's Disease but Not Alzheimer's Disease.

The Key Factors Predicting Dementia in Individuals With Alzheimer's Disease-Type Pathology.

Periodontitis induces endothelial dysfunction in mice.

The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing

Author Correction: Defining early changes in Alzheimer's disease from RNA sequencing of brain regions differentially affected by pathology.

Collaborators (15)

Julia Stevens

Consuelo Walss‐Bass

Mark Larance

Asipu Sivaprasadarao

Caine Smith

Paul Austin

Andrew Tsatsanis

Kerstin Lenk

Ellis Patrick

Joerg Eberhard

Eloise Kok

James Conigrave

Lezanne Ooi

Christine L Paul

Anthony S. Don

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