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Gabriella Scarlatti

Has grant

Director of research group

Ospedale San Raffaele

Italy

Research Interests

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Professors in Italy Professors in Immunology Immunology professors in Italy

Recent Grants

Grant: Open

PedMAb1 Ex: A Phase I Study to Determine Safety and Pharmacokinetics of Potent and Broadly Neutralizing anti-HIV-1 Monoclonal Antibodies (bNAbs) administered to HIV-exposed neonates and infants born without HIV.

Open Date: 2026-01-01

Close Date: 2029-01-01

Grant: Open

EPIVINF Epigenetic regulation of host factors in viral infections

Open Date: 2022-01-01

Close Date: 2027-01-01

Grant: Close

PedMAb Phase I study to determine Safety and Pharmacokinetics of subcutaneous administration of potent and broadly neutralizing anti-HIV-1 monoclonal antibodies (bNAbs), given to HIV-1 exposed uninfected (HEU) neonates and infants.

Open Date: 2021-05-01

Close Date: 2026-03-01

Grant: Close

UMBRELLA- un essai ouvert de phase 1/2 sur la tolérance et la pharmacocinétique de VRC07-523-LS, un anticorps monoclonal neutralisant, puissant et d’action prolongée, dirigé contre le VIH, chez des nourrissons exposés au VIH-1 en Afrique.

Open Date: 2021-01-01

Close Date: 2026-01-01

Grant: Close

MucHIV: Mechanisms of inhibition of HIV mucosal transmission by antibodies

Open Date: 2020-01-01

Close Date: 2023-03-01

Articles (15)

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2025

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2023

Collaborators (26)

Aurora Merolla

Vita-Salute San Raffaele University

ITALY

Gabriella Scarlatti

Research Interests

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Recent Grants

Articles (15)

In danger: HIV vaccine research and development in Europe

Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth

Induction of HIV-1-specific antibody-mediated effector functions by native-like envelope trimers in humans

Simian Immunodeficiency Virus-Based Virus-like Particles Are an Efficient Tool to Induce Persistent Anti-SARS-CoV-2 Spike Neutralizing Antibodies and Specific T Cells in Mice

Viral and immune profiles during the first wave of SARS-CoV-2 infection in hospitalized patients in Sardinia, Italy

HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial

The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients’ survival and long COVID

Safety and pharmacokinetics of subcutaneous administration of broadly neutralizing anti-HIV-1 monoclonal antibodies (bNAbs), given to HIV-1 exposed, uninfected neonates and infants: study protocol for a phase I trial

Preventing breast milk HIV transmission using broadly neutralizing monoclonal antibodies: One size does not fit all

The Immunological Profile of SARS-CoV-2 Infection in Children Is Linked to Clinical Severity and Age

Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia

Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens

<i>Ex vivo</i> challenge models for infectious diseases

Human seminal plasma stimulates the migration of CD11c+ mononuclear phagocytes to the apical side of the colonic epithelium without altering the junctional complexes in an ex vivo human intestinal model

Evaluation of a human mucosal tissue explant model for SARS-CoV-2 replication

Collaborators (26)

Aurora Merolla

Julie fox

Christiane MOOG

Cristian Loretelli

Carolina Herrera

Lorenzo Piemonti

Roberta Caccia

Hannah Cheeseman

Daria Trabattoni

FRANCOIS DABIS

Jose Alcami

Roger Le Grand

Felicia Grasso

Vito Lampasona

Rebecca Moore

Pauline Maisonnasse

Nicola Clementi

Antonella Amendola

Fiona Limanaqi

Mara Biasin

claudio fenizia

Alberto Carocci

CLAUDIA VANETTI

Christian Brander

Sheena McCormack

Chiara Foglieni

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