Gareth Lycett

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Lecturer

Liverpool School of Tropical Medicine

United Kingdom

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About

Gareth Lycett is a Lecturer at the Liverpool School of Tropical Medicine in the United Kingdom. His research encompasses synthetic biology, transgene expression in insects, and insecticide resistance mechanisms, particularly in mosquito vectors such as Aedes aegypti and Anopheles gambiae. Recent publications highlight his work on novel screening platforms for insecticides and potential vector-borne virus transmission in temperate climates.

Recent Grants

Grant: Close

The role of chemosensory proteins in conferring pyrethroid resistance

Open Date: 2021-03-31

Close Date: 2024-03-31

Grant: Close

Preemptive discovery of insecticide cross-resistance mechanisms for next generation malaria control products

Open Date: 2021-02-01

Close Date: 2024-01-31

Grant: Close

Zika: susceptibility of South American and European vectors to ZIKV infection, and influenceof temperature

Open Date: 2016-03-30

Close Date: 2017-09-30

Grant: Close

Zika: susceptibility of South American and European vectors to ZIKV infection, and influenceof temperature

Open Date: 2016-03-30

Close Date: 2017-09-30

Grant: Close

Functional genetic analysis of insecticide resistance in Anopheles gambae

Open Date: 2013-10-01

Close Date: 2016-09-01

Articles (10)

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2024

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2024

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2021

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2021

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2021

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2021

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2020

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2020

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UNITED KINGDOM

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Martin Donnelly

Professor of Evolutionary Genetics

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Gareth Lycett

Research Interests

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About

Recent Grants

Articles (10)

A Synthetic Biology Approach to Transgene Expression in Insects

Aedes aegypti CCEae3A carboxylase expression confers carbamate, organophosphate and limited pyrethroid resistance in a model transgenic mosquito

Actions of Camptothecin Derivatives on Larvae and Adults of the Arboviral Vector <i>Aedes aegypti</i>

Automated phenotyping of mosquito larvae enables high-throughput screening for novel larvicides and offers potential for smartphone-based detection of larval insecticide resistance

CRISPR/Cas9 modified An. gambiae carrying kdr mutation L1014F functionally validate its contribution in insecticide resistance and combined effect with metabolic enzymes

Using the GAL4-UAS System for Functional Genetics in Anopheles gambiae.

New insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids.

Laboratory transmission potential of British mosquitoes for equine arboviruses.

Potential for Zika virus transmission by mosquitoes in temperate climates.

Isolation and transcriptomic analysis of Anopheles gambiae oenocytes enables the delineation of hydrocarbon biosynthesis

Collaborators (6)

Frederick Partridge

Mark John Ingraham Paine

David Sattelle

Philip Leftwich

Rachel McKendry

Martin Donnelly

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