Geert Bultynck

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Full Professor

KU Leuven

Belgium

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About

Geert Bultynck is a Full Professor at KU Leuven in Belgium. His research focuses on cell death and survival mechanisms, particularly involving endoplasmic reticulum and mitochondria interactions, as well as calcium signaling in cellular functions. He has contributed to numerous recent articles examining the roles of proteins and pathways in disease and cellular homeostasis.

Recent Grants

Grant: Close

The BH4 domain of Bcl-2 as a novel target for the development of peptidomimetic molecules that trigger pro-apoptotic Ca2+ signals

Open Date: 2011-01-01

Close Date: 2014-12-01

Grant: Close

A multi-disciplinary approach to provoke pro-apoptotic Ca2+ signals as a novel anti-cancer strategy

Open Date: 2010-10-01

Close Date: 2014-09-01

Articles (18)

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2025

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2021

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2021

Collaborators (5)

Paco Hulpiau

Lecturer and research coordinator

BELGIUM

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Peter Vandenberghe

BELGIUM

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Antigoni Diokmetzidou

University of Padua

ITALY

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Hywel Roderick

Professor

KU Leuven

BELGIUM

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Luc Leybaert

Professor of Physiology

Ghent University

BELGIUM

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Geert Bultynck

Research Interests

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About

Recent Grants

Articles (18)

Author Correction: Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis

Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis

VDAC1 as Janus in cell death and survival: Annexin A5 to the rescue

STIMulating IRE1: How store-operated Ca2+ entry intersects with ER proteostasis

Sustainability in a broad sense: An essential aspect of scientific conferences

10th European Calcium Society symposium: The Ca2+-signaling toolkit in cell function, health and disease

Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments

LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner

Pore-forming proteins as drivers of membrane permeabilization in cell death pathways

The Complex Effects of PKM2 and PKM2:IP3R Disruption on Intracellular Ca2+ Handling and Cellular Functions

Loss of INPP5K attenuates IP3-induced Ca2+ responses in the glioblastoma cell line U-251 MG cells

Allosteric cross-talk between the hydrophobic cleft and the BH4 domain of Bcl-2 in control of inositol 1,4,5-trisphosphate receptor activity

Dysregulated Ca2+ Homeostasis as a Central Theme in Neurodegeneration: Lessons from Alzheimer’s Disease and Wolfram Syndrome

RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes

Keeping an eye on Ca2+ signalling to tackle dry eye diseases

Uniting the divergent Wolfram syndrome–linked proteins WFS1 and CISD2 as modulators of Ca 2+ signaling

I scream for ice cream – TRPC5 as cold sensor in teeth

BIRD-2, a BH4-domain-targeting peptide of Bcl-2, provokes Bax/Bak-independent cell death in B-cell cancers through mitochondrial Ca2+-dependent mPTP opening

Collaborators (5)

Paco Hulpiau

Peter Vandenberghe

Antigoni Diokmetzidou

Hywel Roderick

Luc Leybaert

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