Hywel Roderick

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KU Leuven

Belgium

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Regulation of InsP3-evoked Ca2+ release by accessory proteins

Open Date: 2005-01-01

Close Date: 2012-09-01

Grant: Close

Interactions between the epigenome and signal transduction cascades underlie cardiac remodeling and regeneration.

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Articles (10)

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (11)

Geert Bultynck

Full Professor

KU Leuven

BELGIUM

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Nicolas Rosa

University of Geneva

SWITZERLAND

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Simon Arthur

Professor

University of Dundee

UNITED KINGDOM

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Vijay Rajagopal

Associate Professor

University of Melbourne

AUSTRALIA

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Rosa Doñate Puertas

Université Paris-Saclay

FRANCE

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Guillaume Gilbert

Maitre de Conférence (Teaching Assistant)

Université de Bretagne Occidentale

FRANCE

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Luc Leybaert

Professor of Physiology

Ghent University

BELGIUM

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Wei Liu

The University of Manchester

UNITED KINGDOM

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Bernard Thienpont

Prof. dr. at KU Leuven

KU Leuven

BELGIUM

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Christian Soeller

Professor

University of Bern

SWITZERLAND

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Olaf Bergmann

Karolinska Institutet

SWEDEN

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Hywel Roderick

Research Interests

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Recent Grants

Articles (10)

Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments

Heterogeneity of Repolarization and Cell-Cell Variability of Cardiomyocyte Remodeling Within the Myocardial Infarction Border Zone Contribute to Arrhythmia Susceptibility

InsP<sub>3</sub>R-RyR channel crosstalk augments sarcoplasmic reticulum Ca<sup>2+</sup> release and arrhythmogenic activity in post-MI pig cardiomyocytes.

Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2.

Inositol 1,4,5-trisphosphate receptors in cardiomyocyte physiology and disease

InsP<sub>3</sub>R-RyR Ca<sup>2+</sup> channel crosstalk facilitates arrhythmias in the failing human ventricle.

IP<sub>3</sub>R activity increases propensity of RyR-mediated sparks by elevating dyadic [Ca<sup>2＋</sup>].

The cardiomyocyte firestarter—RyR clusters ignite their neighbours after augmentation of Ca2+ release by β‐stimulation

MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy

Killing in the name of: Reversing epigenetic silencing of ITPR3 to succumb cancer cells' resistance to chemotherapeutics.

Collaborators (11)

Geert Bultynck

Nicolas Rosa

Simon Arthur

Vijay Rajagopal

Rosa Doñate Puertas

Guillaume Gilbert

Luc Leybaert

Wei Liu

Bernard Thienpont

Christian Soeller

Olaf Bergmann

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