George Garinis

Postdoctoral Researcher position at the Institute of Molecular Biology and Biotechnology of the Foundation for Research and Technology-Hellas (FORTH-IMBB) in Heraklion, Greece, working within the InflaCare initiative under the ERA Chair program. The post is part of a research environment led by Prof. Manolis Pasparakis and coordinated by Prof. George Garinis . The InflaCare Team focuses on the impact of DNA damage on innate immune activation and its relevance to age-related inflammatory disorders . The successful candidate will support the scientific implementation of the project and contribute across the work packages and deliverables. This appointment sits within a broader effort to strengthen the institute’s research capacity, foster collaboration, and advance inflammation research through the InflaCare team. The role is embedded in an EU-funded programme under Horizon Europe and is intended for a motivated researcher with strong laboratory and genomic analysis experience.

The Foundation for Research and Technology-Hellas (FORTH), through its Institute of Molecular Biology and Biotechnology (IMBB), invites applications for a postdoctoral researcher position in the Genome (In)stability and Mammalian Physiology group, led by Prof. George Garinis. This opportunity is part of the Hevolution Foundation Geroscience Research Opportunities program, focusing on the project “Targeting genome stability as root cause of aging.” The Garinis Lab investigates the impact of DNA damage on mammalian physiology during aging and its role in the premature onset of age-related diseases. The lab utilizes genetically engineered mouse models with defects in nucleotide excision repair and/or transcription, as well as mice expressing tagged DNA repair proteins. These models are combined with high-throughput, biochemical, molecular, and cellular biology methods to understand how mammalian cells counteract DNA damage-driven pathologies and prolong healthspan. The current project aims to uncover the mechanisms of DNA repair gene regulation, particularly focusing on the DREAM complex as a master regulator of DNA repair capacities. The research will explore the evolutionary trade-offs of somatic DNA repair, the fitness costs of enhanced repair, and how DREAM inhibition may extend healthspan in mammals. The successful candidate will address these questions using advanced molecular and cellular biology techniques, mouse genetics, and bioimaging. Applicants must have a BSc, MSc, and PhD in Biology, Medicine, Life Sciences, or related fields, with over 8 years of experience in DNA damage research in mammalian physiology and aging. A strong publication record (at least 5 papers in high-impact journals), certification in animal handling (e.g., FELASA), and fluency in English are required. Experience in nucleic acid processing, biochemical and molecular techniques, cell culture, and bioimaging is highly desirable. Participation in international scientific meetings and the ability to design, manage, and conduct research initiatives are considered assets. The position offers a 3-month contract with the possibility of extension, and salary will be determined according to experience and Greek legislation. The anticipated start date is January 1, 2026. Applications should be submitted electronically by November 20, 2025, and must include the application form, CV, statement of purpose, contact details of two referees, and scanned copies of academic titles and qualifications. Shortlisted candidates will be invited for an interview, and the selection process will be based on a detailed evaluation of qualifications and experience. For more information about the lab, visit https://www.garinislab.gr/ . The official call and application details can be found at Euraxess and the IMBB website. For inquiries, contact [email protected].

The Foundation for Research and Technology-Hellas (FORTH), through its Institute of Molecular Biology and Biotechnology (IMBB), is seeking a Postdoctoral Researcher to join the InflaCare Project, funded by Horizon Europe. The InflaCare Team, led by Prof. Manolis Pasparakis (ERA Chair holder) and coordinated by Prof. George Garinis, investigates the impact of DNA damage on innate immune activation and its relevance to age-related inflammatory disorders. The project aims to enhance IMBB's research capacity, attract top-tier researchers, and foster collaborations that advance research and innovation in inflammation biology. The successful candidate will assist with all work packages and deliverables of the InflaCare Project, contributing to cutting-edge research in molecular biology, biochemistry, and immunology. The position is based in Heraklion, Greece, and offers a 12-month contract with the possibility of extension, with salary and benefits determined by experience and Greek legislation. Applicants must have a strong background in biological sciences, with a BSc, MSc, and PhD in relevant fields, and over three years of research experience in molecular/biochemical techniques, flow cytometry, cell cultures, and imaging, particularly in the context of inflammation, immune responses, and DNA damage in mammalian cells and mouse models. Excellent English language skills and a FELASA or equivalent certificate for animal handling are required, as well as a record of peer-reviewed publications in high-impact journals. Desired qualifications include participation in international scientific meetings and experience with a range of laboratory techniques. Applications should be submitted electronically by November 17, 2025, and must include an application form, CV, statement of purpose, contact details for two referees, and scanned copies of academic titles and qualifications. The selection process involves evaluation by a committee, with shortlisted candidates invited for an interview. The project offers an opportunity to contribute to impactful research in inflammation and ageing, within a dynamic and innovative research environment at one of Greece's leading scientific institutes.