Giuseppe Melacini

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Professor

McMaster University

Canada

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Recent Grants

Grant: Close

Structural Basis of Cyclic Nucleotide Signal Translation

Open Date: 2023-04-01

Close Date: 2024-03-01

Grant: Close

In Situ NMR Studies of Plasma Protein Dynamics and Interactions

Open Date: 2019-04-01

Close Date: 2024-04-01

Grant: Close

Integrated liquid chromatography-multiangle light scattering system to measure absolute masses and stoichiometries of biological assemblies in solution

Open Date: 2019-04-01

Close Date: 2021-04-01

Grant: Close

Structural Basis of Cyclic Nucleotide Signal Translation and Inhibition

Open Date: 2018-04-01

Close Date: 2023-03-01

Grant: Close

Mapping the Effect of Fatty Acids on Albumin-Drug Interactions by NMR

Open Date: 2018-02-01

Close Date: 2018-07-01

Articles (11)

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (2)

Dushyant Jahagirdar

CANADA

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Maikel Rheinstadter

Professor

McMaster University

CANADA

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Giuseppe Melacini

Research Interests

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Recent Grants

Articles (11)

Amyloid-driven allostery

Fractionation Factors Reveal Hidden Frustration in an Ancient Allosteric Module

Allosteric regulation of cyclic nucleotide-dependent protein kinases

Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases

An auto-inhibited state of protein kinase G and implications for selective activation

Identification of core allosteric sites through temperature- and nucleus-invariant chemical shift covariance

Allosteric pluripotency: challenges and opportunities

Erythro-VLPs: Anchoring SARS-CoV-2 spike proteins in erythrocyte liposomes

Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G

Interactions of intrinsically disordered proteins with the unconventional chaperone human serum albumin: From mechanisms of amyloid inhibition to therapeutic opportunities

Structural determinants of the interactions of catechins with Aβ oligomers and lipid membranes

Collaborators (2)

Dushyant Jahagirdar

Maikel Rheinstadter

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