Gordon Freeman

Professor

Dana-Farber Cancer Institute

United States

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About

Professor Gordon Freeman is affiliated with Dana Farber Cancer Institute in the United States. His research primarily focuses on tumor immunology, specifically investigating the mechanisms of immune evasion in cancer through various pathways such as PD-1 and mTOR. His recent publications include studies on cGAS methylation, T cell exhaustion, and the implications of PD-L1 expression in response to immunotherapy.

Articles (10)

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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UNITED STATES

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Gordon Freeman

Research Interests

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About

Articles (10)

mTOR regulates T cell exhaustion and PD-1–targeted immunotherapy response during chronic viral infection

PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma

PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

Soluble PD-L1 as an early marker of progressive disease on nivolumab

PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 + T cells in lymphoid tissue

Emerging concepts in PD-1 checkpoint biology

Retinoblastoma protein expression and its predictors in triple-negative breast cancer

The importance of exosomal PDL1 in tumour immune evasion

Collaborators (6)

David Kwiatkowski

David Braun

Suresh Ramalingam

Xiaoming Dai

Chen Chu

David McDermott

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