Xiaoming Dai

Assistant Professor

Beth Israel Deaconess Medical Center

United States

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Articles (10)

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Collaborators (3)

Gordon Freeman

Professor

Dana-Farber Cancer Institute

UNITED STATES

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Zhen Wang

Beth Israel Deaconess Medical Center

UNITED STATES

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Chen Chu

Dana-Farber Cancer Institute

UNITED STATES

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Xiaoming Dai

Research Interests

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Articles (10)

PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1

Amino acid availability governs mTOR ubiquitination.

PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2.

Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.

Lactate fuels mitosis.

Mitochondrial PD-L1 modulates cancer immunotherapy.

AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation.

Ring domains are essential for GATOR2-dependent mTORC1 activation.

S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions.

Collaborators (3)

Gordon Freeman

Zhen Wang

Chen Chu

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