Gordon Moran

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University of Nottingham

United Kingdom

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Recent Grants

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Nottingham/Astra ZenecA prospective IBD cohort study

Open Date: 2021-12-01

Close Date: 2024-06-01

Grant: Close

The MERIT pilot study: Towards Precision Medicine: a MagnEtic Resonance Imaging-based measure of fibrosis in enTeric Crohn’s disease

Open Date: 2021-01-01

Close Date: 2022-04-01

Grant: Close

Targeting a Cxcl10-approach in Ulcerative Colitis

Open Date: 2021-01-01

Close Date: 2022-10-01

Grant: Close

Stopping Aminosalicylate Therapy in Inactive Crohn’s Disease Study: A Randomized, Open-label, Non-inferiority

Open Date: 2021-01-01

Close Date: 2025-12-01

Grant: Close

Feasibility of a quantitative MRI protocol for the assessment of inflammation in Ulcerative Colitis

Open Date: 2020-04-01

Close Date: 2022-03-01

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Collaborators (24)

Tim Raine

Cambridge University Hospitals NHS Foundation Trust

UNITED KINGDOM

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Glen Doherty

UCD Full Clinical Professor

Dublin City University

IRELAND

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Philip Atherton

Professor of Clinical, Metabolic & Molecular Physiology

University of Nottingham

UNITED KINGDOM

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James Lindsay

Professor of Inflammatory Bowel Disease.

Queen Mary University of London

UNITED KINGDOM

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Shahida Din

University of Edinburgh

UNITED KINGDOM

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Sreedhar Subramanian

UNITED KINGDOM

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Susan T. Francis

University of Nottingham

UNITED KINGDOM

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Maurice B Loughrey

UNITED KINGDOM

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Alan Graham Pockley

Emeritus Professor of Immunobiology

University of Nottingham

UNITED KINGDOM

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Christopher Probert

Professor of Gastroenterology

University of Liverpool

UNITED KINGDOM

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Rachel Cooney

Honorary Senior Lecturer

University of Birmingham

UNITED KINGDOM

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Simon Bond

UNITED KINGDOM

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Thomas Butler

The University of Manchester

UNITED KINGDOM

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Caroline L. Hoad

UNITED KINGDOM

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Matthew Jacques

Assistant Professor

University of Nottingham

UNITED KINGDOM

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Pardeep Pabla

University of Nottingham

UNITED KINGDOM

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Luca Marciani

Professor in Gastrointestinal Imaging

University of Nottingham

UNITED KINGDOM

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Penny Gowland

Professor at University of Nottingham

University of Nottingham

UNITED KINGDOM

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Vassiliki Sinopoulou

University of Central Lancashire

UNITED KINGDOM

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Craig Mowat

Academic, Clinical Sen Lecturer/Honorary Cons (Teaching and Research)

University of Dundee

UNITED KINGDOM

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Sally Eldeghaidy

Assistant Professor

University of Nottingham

UNITED KINGDOM

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Professor Laith Alrubaiy

Swansea University

UNITED KINGDOM

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Simon P L Travis

UNITED KINGDOM

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Christopher A. Lamb

UNITED KINGDOM

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Gordon Moran

Research Interests

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Recent Grants

Articles (30)

Immunomodulators and Advanced Therapies for Induction of Remission in Crohn’s Disease: A Systematic Review and Network Meta-Analysis

Small Bowel Motility Quantified by Cine MRI to Predict Longer-Term Response in Patients with Crohn’s Disease Commencing Biological Therapy: The Motility Study

Beyond the guideline: lessons in leadership, limits and legacy from the BSG IBD process.

British Society of Gastroenterology guidelines on inflammatory bowel disease in adults: 2025.

Developing an adaptive platform trial for evaluation of medical treatments for Crohn's disease.

Inter- and intra-observer variability of software quantified bowel motility measurements of small bowel Crohn's disease: findings from the MOTILITY trial.

Developing IBD Outcome Effect Size Thresholds to Inform Research, Guidelines, and Clinical Decisions

Designing a multi-arm, multi-stage platform trial for venous leg ulceration - Venous leg ulcers: management and eradication, the VEIN platform study.: Designing a platform/adaptive trial for venous leg ulcers (VLU) - The VEIN platform.

Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial.

Defining Radiological Healing in Perianal Fistulizing Crohn's Disease: a TOpClass Global Expert Delphi Consensus.

A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial

Prepublication abstract-only reports compared with full-text manuscripts for randomised controlled trials in inflammatory bowel disease: a systematic review

Substantial cost savings of ultrasound-based management over magnetic resonance imaging-based management in an inflammatory bowel disease service.

Association between body mass index and age of disease onset with clinical outcomes in paediatric-onset Crohn's Disease (CD): a UK nation-wide analyses using the NIHR-IBD BioResource.

Determining the optimal treatment target in patients with ulcerative colitis: rationale, design, protocol and interim analysis for the randomised controlled VERDICT trial.

Infliximab for maintenance of medically-induced remission in Crohn's disease.

Safety and efficacy of autologous haematopoietic stem-cell transplantation with low-dose cyclophosphamide mobilisation and reduced intensity conditioning versus standard of care in refractory Crohn's disease (ASTIClite): an open-label, multicentre, randomised controlled trial.

Digital pathology for reporting histopathology samples, including cancer screening samples - definitive evidence from a multisite study.

MRI tagging of colonic chyme mixing in healthy subjects: Inter‐observer variability and reliability of the measurement with time

BSG 2024 IBD guidelines protocol (standard operating procedures)

Systematic review: Sarcopenia in paediatric inflammatory bowel disease

Systematic review with meta‐analysis: Medical therapies for treatment of ulcerative proctitis

Systematic review of sarcopenia in inflammatory bowel disease

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

An examination of resting-state functional connectivity in patients with active Crohn's disease.

Biologic therapy for inflammatory bowel disease: Real-world comparative effectiveness and impact of drug sequencing in 13,222 patients within the UK IBD BioResource.

The relationship between Central Nervous System morphometry changes and key symptoms in Crohn’s disease

Acute effects of prior dietary fat ingestion on postprandial metabolic responses to protein and carbohydrate co-ingestion in overweight and obese men: A randomised crossover trial

Imaging in inflammatory bowel disease: current and future perspectives

Establishment of a validated central reading system for ileocolonoscopy in an academic setting

Collaborators (24)

Tim Raine

Glen Doherty

Philip Atherton

James Lindsay

Shahida Din

Sreedhar Subramanian

Susan T. Francis

Maurice B Loughrey

Alan Graham Pockley

Christopher Probert

Rachel Cooney

Simon Bond

Thomas Butler

Caroline L. Hoad

Matthew Jacques

Pardeep Pabla

Luca Marciani

Penny Gowland

Vassiliki Sinopoulou

Craig Mowat

Sally Eldeghaidy

Professor Laith Alrubaiy

Simon P L Travis

Christopher A. Lamb

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