Luca Marciani

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Professor in Gastrointestinal Imaging

University of Nottingham

United Kingdom

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About

Professor Luca Marciani is a faculty member in Gastrointestinal Imaging at the University of Nottingham, UK. His research primarily focuses on the application of magnetic resonance imaging (MRI) in gastrointestinal studies, examining aspects such as colonic function, gut microbiota interaction, and novel imaging techniques. Recent articles include investigations into the effects of dietary interventions and the biomechanics of constipation.

Recent Grants

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Gut Imaging for Function and Transit in CF – GIFT-CF 3: an evaluation of triple combination therapy

Open Date: 2020-10-01

Close Date: 2022-03-01

Grant: Close

A phase IV, crossover, randomized, double blind and placebo-controlled clinical trial to evaluate the mode of action of a single dose of Dulcolax® in patients with occasional constipation - Single dose trial and multiple dose trial

Open Date: 2019-10-01

Close Date: 2022-10-01

Grant: Close

Assessment of gut transit in paediatric constipation without ionizing radiation: Magnetic Resonance Imaging transit mini-capsules and methods 2 (MAGIC2)

Open Date: 2019-07-01

Close Date: 2022-06-01

Grant: Close

Gut Imaging for Function and Transit in CF – the GIFT CF study

Open Date: 2018-08-01

Close Date: 2020-07-01

Grant: Close

Understanding the mechanisms for the variation in beneficial effects of dietary fibre in Irritable Bowel Syndrome (IBS): an old concept in new light

Open Date: 2016-07-01

Close Date: 2019-06-01

Articles (23)

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Collaborators (30)

nicole clemence roy

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University of Otago

NEW ZEALAND

Luca Marciani

Research Interests

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Recent Grants

Articles (23)

Magnetic Resonance Imaging Reveals Novel Insights into the Dual Mode of Action of Bisacodyl: A Randomized, Placebo‐controlled Trial in Constipation

Assessing Water Content of the Human Colonic Chyme Using the MRI Parameter T1: A Key Biomarker of Colonic Function

Mode of Action of Psyllium in Reducing Gas Production from Inulin and its Interaction with Colonic Microbiota: A 24-hour, Randomized, Placebo-Controlled Trial in Healthy Human Volunteers

Novel Use of Manganese Gluconate as a Marker for Visualization of Tablet Dissolution in the Fed Human Stomach Using Magnetic Resonance Imaging

Combined MRI, high-resolution manometry and a randomised trial of bisacodyl versus hyoscine show the significance of an enlarged colon in constipation: the RECLAIM study

Development of Resorbable Phosphate-Based Glass Microspheres as MRI Contrast Media Agents

Intra‐ and interindividual variability in fasted gastric content volume

Use of Magnetic Resonance Imaging for Visualization of Oral Dosage Forms in the Human Stomach: A Scoping Review

A longitudinal study assessing the impact of elexacaftor/tezacaftor/ivacaftor on gut transit and function in people with cystic fibrosis using magnetic resonance imaging (MRI)

One Year of Gluten-Free Diet Impacts Gut Function and Microbiome in Celiac Disease

Structuring white rice with gellan gum reduces the glycemic response in healthy humans

Experimental Measurements of the Length of the Human Colon: A Systematic Review and Meta-Analysis

MRI tagging of colonic chyme mixing in healthy subjects: Inter‐observer variability and reliability of the measurement with time

Heat Treatment of Bovine Milk Impacts Gastric Emptying and Nutrient Appearance

Reducing starch digestibility of white rice by structuring with hydrocolloids

Correction: Schütt et al. Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model. Pharmaceutics 2022, 14, 184

Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research

Application of In Vivo MRI Imaging to Track a Coated Capsule and Its Disintegration in the Gastrointestinal Tract in Human Volunteers

Simulating the Hydrodynamic Conditions of the Human Ascending Colon: A Digital Twin of the Dynamic Colon Model

Medical Device Development for Children and Young People&mdash;Reviewing the Challenges and Opportunities

Diagnostic Accuracy of Non-Invasive Imaging for Detection of Colonic Inflammation in Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

Size and Number of Food Boluses in the Stomach after Eating Different Meals: Magnetic Resonance Imaging Insights in Healthy Humans

Luminal Fluid Motion Inside an In Vitro Dissolution Model of the Human Ascending Colon Assessed Using Magnetic Resonance Imaging

Collaborators (30)

nicole clemence roy

Christabella Ng

Dileep N Lobo

Snjezana Snow Stolnik

Alan Smyth

Sophia G. Antimisiaris

Konstantinos Stamatopoulos

Carol Coupland

Warren McNabb

Caroline L. Hoad

robin spiller

Giles Major

Mark Simmons

Floris Ernst

Ourania Gouseti

Hans Lennernäs

Penny Gowland

Aaron Courtenay

Nunzio Denora

Gordon Moran

Timothy Angeli-Gordon

Christophe Matthys

Samson Nivins

Richard F. Mithen

Pavel Gershkovich

Joshua Reid

Colin J. Crooks

Peter Fryer

Ifty Ahmed

Mirko Koziolek

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Medical Device Development for Children and Young People—Reviewing the Challenges and Opportunities