Graça Soveral

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Full Professor

Universidade de Lisboa Faculdade de Farmácia

Portugal

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About

Graça Soveral is a Full Professor at Universidade de Lisboa Faculdade de Farmácia in Portugal. Her research focuses on aquaporins and their roles in cancer development, cell biophysics, and inflammation. Recent publications highlight the differential modulation of cell properties by aquaporins and their potential as prognostic biomarkers in pancreatic cancer. She also explores the therapeutic potential of organogold complexes in oncology and the involvement of aquaporins in various physiological processes.

Recent Grants

Grant: Close

Aquaporin-9 Immuno-Therapy: a new strategy for reducing inflammation

Open Date: 2023-01-01

Close Date: 2026-01-01

Grant: Close

Aquaporin-9 Immuno-Therapy: a new strategy for reducing inflammation

Open Date: 2023-01-01

Close Date: 2026-01-01

Grant: Close

AQUA3-4MEL - Targeting aquaporin-3 as a novel therapeutic approach for melanoma

Open Date: 2018-10-01

Close Date: 2021-09-01

Grant: Close

AQUA3-4MEL - Targeting aquaporin-3 as a novel therapeutic approach for melanoma

Open Date: 2018-10-01

Close Date: 2021-09-01

Grant: Close

PAINSpot - Deal with PAINS: strategies to spot membrane modulators

Open Date: 2018-01-01

Close Date: 2021-01-01

Articles (16)

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2025

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2023

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2023

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2022

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2022

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2022

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2022

Collaborators (10)

Victoria Catalan

Clinica Universidad de Navarra

SPAIN

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Amaia Rodríguez

Clinica Universidad de Navarra

SPAIN

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Nuno Santos

Instituto de Medicina Molecular

PORTUGAL

SPAIN

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Maria Rita Azevedo e Castro

Research Assistant Professor

Penn State

UNITED STATES

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Graça Soveral

Research Interests

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About

Recent Grants

Articles (16)

Aquaporin‐1, aquaporin‐3 and aquaporin‐5 differentially modulate cell biophysical and biomechanical properties, impacting cell stiffness and cell–cell adhesion

The Association of Aquaporins with MAPK Signaling Pathway Unveils Potential Prognostic Biomarkers for Pancreatic Cancer: A Transcriptomics Approach

The Expanding Role of Aquaporin-1, Aquaporin-3 and Aquaporin-5 as Transceptors: Involvement in Cancer Development and Potential Druggability

Liposomal Formulation of an Organogold Complex Enhancing Its Activity as Antimelanoma Agent—In Vitro and In Vivo Studies

Peroxiporins and Oxidative Stress: Promising Targets to Tackle Inflammation and Cancer

Blockage of aquaporin‐3 peroxiporin activity by organogold compounds affects melanoma cell adhesion, proliferation and migration

Increased Aquaporin-7 Expression Is Associated with Changes in Rat Brown Adipose Tissue Whitening in Obesity: Impact of Cold Exposure and Bariatric Surgery

Aquaporins Transcripts with Potential Prognostic Value in Pancreatic Cancer

AQP3-Dependent PI3K/Akt Modulation in Breast Cancer Cells

Aquaporins in Obesity

Tissue-Specific Variation in Aquaporins and Cytokines Transcriptional Profiles in Piglets being LPS Challenged

Unraveling the Aquaporin-3 Inhibitory Effect of Rottlerin by Experimental and Computational Approaches

The Effect of Nutritional Ketosis on Aquaporin Expression in Apolipoprotein E-Deficient Mice: Potential Implications for Energy Homeostasis

Aquaporin-3 and Aquaporin-5 Facilitate Migration and Cell–Cell Adhesion in Pancreatic Cancer by Modulating Cell Biomechanical Properties

CFTR modulates aquaporin-mediated glycerol permeability in mouse Sertoli cells

Aquaglyceroporin Modulators as Emergent Pharmacological Molecules for Human Diseases

Collaborators (10)

Victoria Catalan

Amaia Rodríguez

Nuno Santos

Bruno L. Victor

A C Ross

Pedro Fontes Oliveira

Jorge Paulino

Filomena Carvalho

Gema Frühbeck

Maria Rita Azevedo e Castro

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