Gunnar Hargus, MD PhD

Assistant Professor

Columbia University Irving Medical Center

United States

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Gunnar Hargus, MD PhD, is an Assistant Professor at Columbia University Irving Medical Center in the United States. His research focuses on neurodegenerative diseases, particularly Alzheimer's disease and frontotemporal dementia, through the use of induced pluripotent stem cell models. He is also investigating the interplay between SARS-CoV-2 related microglial reactivity and astrocyte pathology, as well as the epitranscriptomic regulation of tau phosphorylation and clinical applications of genome sequencing in complex medical cases.

Articles (10)

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2020

Collaborators (3)

Sachin Jambawalikar

Chief of Medical Physics/ Assist. Professor of Radiology

Columbia University

UNITED STATES

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Caghan Kizil

Associate Professor

Columbia University

UNITED STATES

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Andrew Teich

Columbia University Columbia College

UNITED STATES

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Gunnar Hargus, MD PhD

Research Interests

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Articles (10)

Induced pluripotent stem cell models as a tool to investigate and test fluid biomarkers in Alzheimer's disease and frontotemporal dementia.

The link between SARS-CoV-2 related microglial reactivity and astrocyte pathology in the inferior olivary nucleus.

RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

Clinical Real-Time Genome Sequencing to Solve the Complex and Confounded Presentation of a Child With Focal Segmental Glomerulosclerosis and Multiple Malignancies.

Molecular Insights into Cell Type-specific Roles in Alzheimer's Disease: Human Induced Pluripotent Stem Cell-based Disease Modelling.

COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital.

Human Induced Pluripotent Stem Cell Models of Frontotemporal Dementia With Tau Pathology.

Synchronous supratentorial and infratentorial oligodendrogliomas with incongruous IDH1 mutations, a case report.

Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons.

Neuronophagia and microglial nodules in a SARS-CoV-2 patient with cerebellar hemorrhage.

Collaborators (3)

Sachin Jambawalikar

Caghan Kizil

Andrew Teich

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