Han-Ming Shen

Visiting Professor

National University of Singapore (NUS)

Singapore

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Han-Ming Shen is a Visiting Professor at the National University of Singapore. His research primarily focuses on macrophage plasticity, autophagy, and the molecular mechanisms underlying neurodegenerative diseases and cancer. Recent publications include work on mitophagy and its implications in Alzheimer's disease, as well as the regulation of stemness in non-small cell lung cancer (NSCLC). He contributes to advancing understanding of autophagy-dependent mechanisms and their potential therapeutic applications.

Articles (18)

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2024

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2022

Collaborators (5)

Gabor Juhasz

Full Professor (part-time)

Eötvös Loránd Tudományegyetem Biológiai Intézet

HUNGARY

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Scott Ayton

University of Melbourne

AUSTRALIA

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Werner J.H. Koopman

Associate professor

Radboud University Medical Center

NETHERLANDS

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Hans‐Uwe Simon

SWITZERLAND

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Jon Lane

University of Bristol

UNITED KINGDOM

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Han-Ming Shen

Research Interests

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About

Articles (18)

International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis.

Macrophage plasticity: signaling pathways, tissue repair, and regeneration.

Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model.

Linc00673-V3 positively regulates autophagy by promoting Smad3-mediated <i>LC3B</i> transcription in NSCLC.

FBP1 inhibits NSCLC stemness by promoting ubiquitination of Notch1 intracellular domain and accelerating degradation.

Targeting mitophagy as a novel therapeutic approach in liver cancer

Donut and spheroid mitochondria: eating, regenerating or trash them out?

TMEM251, a new player in lysosomal enzyme trafficking

The emerging mechanisms and functions of microautophagy

Autophagic secretion of mitochondria (ASM): an alternative way for getting rid of damaged mitochondria

CLN3 clinches lysosomes in clearance of glycerophospholipids

A novel mitochondrial quality control pathway: Autophagic secretion of mitochondria (ASM)

Enhancement of efferocytosis through biased FPR2 signaling attenuates intestinal inflammation.

Low dose PFDA induces DNA damage and DNA repair inhibition by promoting nuclear cGAS accumulation in ovarian epithelial cells.

Chemical mitophagy modulators: Drug development strategies and novel regulatory mechanisms.

Photocatalytic Pt(IV)‐Coordinated Carbon Dots for Precision Tumor Therapy

Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19.

Autophagy in health and disease: From molecular mechanisms to therapeutic target.

Collaborators (5)

Gabor Juhasz

Scott Ayton

Werner J.H. Koopman

Hans‐Uwe Simon

Jon Lane

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