Hannes Mutschler

Full Professor

Technische Universität Dortmund

Germany

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Hannes Mutschler is a Full Professor at Technische Universität Dortmund, Germany. His research areas include RNA-peptide interactions, the design of synthetic RNA replicons, and the study of membraneless protocells. He has published recent articles focusing on RNA catalysis, coacervate microdroplets, and computational design of ribozymes.

Articles (17)

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2025

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2023

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2022

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2022

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2021

Collaborators (4)

Lars Hubatsch

Max Planck Institute of Molecular Cell Biology and Genetics

GERMANY

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Sheref Mansy

Professor

University of Alberta

CANADA

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Job Boekhoven

Professor

Technical University of Munich

GERMANY

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Dieter Braun

Ludwig Maximilian University of Munich

GERMANY

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Hannes Mutschler

Research Interests

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Articles (17)

Membraneless protocell confined by a heat flow

RNA-peptide interactions tune the ribozyme activity within coacervate microdroplet dispersions

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes

Protein-free catalysis of DNA hydrolysis and self-integration by a ribozyme

Regulating Nucleic Acid Catalysis Using Active Droplets

Regulierung von Nukleinsäurekatalyse mit aktiven Koazervaten

Design of Novel Synthetic RNA Replicons Based on Emesvirus zinderi

Ribozyme activity modulates the physical properties of RNA–peptide coacervates

Design principles and applications of synthetic self‐replicating RNAs

Engineering a Synthetic RNA Segregation System

The Long Road to a Synthetic Self-Replicating Central Dogma

Ribozyme-mediated RNA synthesis and replication in a model Hadean microenvironment

Periodic temperature changes drive the proliferation of self-replicating RNAs in vesicle populations

A Primer on Building Life‐Like Systems

Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning

In vitro characterisation of the MS2 RNA polymerase complex reveals host factors that modulate emesviral replicase activity

Enhanced Ribozyme‐Catalyzed Recombination and Oligonucleotide Assembly in Peptide‐RNA Condensates

Collaborators (4)

Lars Hubatsch

Sheref Mansy

Job Boekhoven

Dieter Braun

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