Sheref Mansy

Professor

University of Alberta

Canada

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Sheref Mansy is a Professor at the University of Alberta, Canada. His research focuses on protocell systems, prebiotic chemistry, and the intersections of biology and material science, as demonstrated in his recent publications. Notable topics include membraneless protocells, iron-sulfur cluster formation, and the role of extracellular vesicles in cancer detection.

Articles (20)

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2025

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2020

Collaborators (14)

Oliver Shorttle

Lecturer

University of Cambridge

UNITED KINGDOM

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Orsetta Quaini

University of Trento

ITALY

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Graziano Guella

Full Professor of Organic Chemistry

University of Trento

ITALY

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Gokhan Unlu

Rockefeller University

UNITED STATES

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HUAN PENG

University of California, Los Angeles

UNITED STATES

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Lingzi Sang

Assistant Professor

University of Alberta

CANADA

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Hannes Mutschler

Full Professor

Technische Universität Dortmund

GERMANY

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Hubertus Haas Haas

Medical University of Innsbruck

AUSTRIA

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Li Zhao

Rockefeller University

UNITED STATES

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Smilja Todorovic

Universidade de Aveiro

PORTUGAL

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Sarah Styler

Assistant Professor, Environmental Chemistry

McMaster University

CANADA

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John D. Lewis

CANADA

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Ramanarayanan Krishnamurthy

Professor

Scripps Research Institute

UNITED STATES

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Dieter Braun

Ludwig Maximilian University of Munich

GERMANY

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Sheref Mansy

Research Interests

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Articles (20)

Membraneless protocell confined by a heat flow

Prebiotic Environmental Conditions Impact the Type of Iron‐Sulfur Cluster Formed

Protometabolically Generated NADH Mediates Material Properties of Aqueous Dispersions to Coacervate Microdroplets

Peptide Mimics of the Cysteine‐Rich Regions of HapX and SreA Bind a [2Fe‐2S] Cluster In Vitro

A Magnesium Binding Site And The Anomeric Effect Regulate The Abiotic Redox Chemistry Of Nicotinamide Nucleotides

Protocellular Heme and Iron–Sulfur Clusters

Model Atmospheric Aerosols Convert to Vesicles upon Entry into Aqueous Solution

Integrating extracellular vesicle and circulating cell‐free DNA analysis using a single plasma aliquot improves the detection of HER2 positivity in breast cancer patients

Cyclophospholipids Enable a Protocellular Life Cycle

Autoregulatory control of mitochondrial glutathione homeostasis.

Histidine Ligated Iron‐Sulfur Peptides

Protometabolism as out-of-equilibrium chemistry

Prebiotic Environments with Mg2+ and Thiophilic Metal Ions Increase the Thermal Stability of Cysteine and Non-cysteine Peptides

Treatment of Wound Infections in a Mouse Model Using Zn2+-Releasing Phage Bound to Gold Nanorods

Racing toward Fast and Effective 17O Isotopic Labeling and Nuclear Magnetic Resonance Spectroscopy of N-Formyl-MLF-OH and Associated Building Blocks

Spectral decomposition of iron-sulfur clusters

Population-Level Membrane Diversity Triggers Growth and Division of Protocells

Protometabolic Reduction of NAD+ with α-Keto Acids

Cell‐Free Synthesis of Dopamine and Serotonin in Two Steps with Purified Enzymes

Artificial cells drive neural differentiation

Collaborators (14)

Oliver Shorttle

Orsetta Quaini

Graziano Guella

Gokhan Unlu

HUAN PENG

Lingzi Sang

Hannes Mutschler

Hubertus Haas Haas

Li Zhao

Smilja Todorovic

Sarah Styler

John D. Lewis

Ramanarayanan Krishnamurthy

Dieter Braun

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