Hans-Dieter Volk

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Seniorprofessor

Charité - Universitätsmedizin Berlin

Germany

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About

Hans-Dieter Volk is a Seniorprofessor at Charité Universitätsmedizin Berlin, Germany. His research areas include gene editing for T cell therapy, immunogenicity of mRNA, and the role of regulatory T cells in immune responses. He has published extensively on the practical applications of biotechnology in health care, including innovative approaches to cancer treatment and biomarker identification in heart failure.

Recent Grants

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ReSHAPE

Open Date: 2019-01-01

Close Date: 2023-12-01

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PACE

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HipGen

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Articles (21)

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2022

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2022

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2022

Collaborators (25)

Dirk Strunk

AUSTRIA

Hans-Dieter Volk

Research Interests

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About

Recent Grants

Articles (21)

Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer.

Practical Applications of Large Language Models for Health Care Professionals and Scientists

Effector memory-type regulatory T cells display phenotypic and functional instability.

In Vitro Transcribed mRNA Immunogenicity Induces Chemokine-Mediated Lymphocyte Recruitment and Can Be Gradually Tailored by Uridine Modification.

Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.

Increased Expression of Proinflammatory Genes in Peripheral Blood Cells Is Associated with Cardiac Cachexia in Patients with Heart Failure with Reduced Ejection Fraction.

Long-term in vitro maintenance of plasma cells in a hydrogel-enclosed human bone marrow microphysiological 3D model system.

PACE: randomized, controlled, multicentre, multinational, phase III study of PLX-PAD for critical limb ischaemia in patients unsuitable for revascularization: randomized clinical trial.

Measuring translational research impact requires reaching beyond current metrics

CAR NK-92 cell–mediated depletion of residual TCR+ cells for ultrapure allogeneic TCR-deleted CAR T-cell products

Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells.

Complex Spatio-Temporal Interplay of Distinct Immune and Bone Cell Subsets during Bone Fracture Healing.

Interleukin 8 in postoperative delirium – Preliminary findings from two studies

A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation.

Batch Effects during Human Bone Marrow Stromal Cell Propagation Prevail Donor Variation and Culture Duration: Impact on Genotype, Phenotype and Function.

Effects of caloric restriction on the gut microbiome are linked with immune senescence.

A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity.

HIPGEN: a randomized, multicentre phase III study using intramuscular PLacenta-eXpanded stromal cells therapy for recovery following hip fracture arthroplasty: a study design.

Human iPSC-Derived Renal Cells Change Their Immunogenic Properties during Maturation: Implications for Regenerative Therapies.

Immuno-cardio-oncology: Killing two birds with one stone?

Local immune cell contributions to fracture healing in aged individuals - A novel role for interleukin 22.

Collaborators (25)

Dirk Strunk

Dimitrios Laurin Wagner

Andreas Kurtz

Julia K. Polansky

Christian Luca Flugel

Insa Feinkohl

Christian H. Bucher

Michael Schmueck-Henneresse

Leila Amini

Peter Turnbaugh

Frank Konietschke

Katharina Schallmoser

Jonas Kath

Radost A. Saß

Viktor Glaser

Sarah Hochmann

David Grainger

Manfred Gossen

Tobias Winkler

Christian G. Huber

Annemarie Lang

Florian Lammers-Lietz

Fatima Halzl-Yürek

Carmen Scheibenbogen

Simon Reinke

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