Haruo Usuda

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University of Western Australia

Australia

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Recent Grants

Grant: Close

人工赤血球を人工胎盤のプライミング液に用いた人工子宮システムの有用性の検討

Open Date: 2021-04-01

Close Date: 2024-03-31

Grant: Close

Elucidation of the mechanism of developmental fetal organ damage caused by stress-induced overmaturation

Open Date: 2015-04-01

Close Date: 2019-03-31

Grant: Close

Development of an artificial placenta for extremely premature infants: pumpless arteriovenous extracorporeal life support in a premature lamb model

Open Date: 2014-04-01

Close Date: 2016-03-31

Articles (16)

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2024

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (7)

Zubair Amin

Senior Consultant. Head

National University Health System

SINGAPORE

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Tsukasa Takahashi

University in Western Australia

AUSTRALIA

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Yusaku Kumagai

Tohoku University Hospital

JAPAN

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Michael Clarke

University of Western Australia

AUSTRALIA

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Jeffrey Keelan

University of Western Australia

AUSTRALIA

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John P. Newnham

AUSTRALIA

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Lucy Furfaro

University of Western Australia

AUSTRALIA

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Haruo Usuda

Research Interests

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Recent Grants

Articles (16)

Antenatal steroids elicited neurodegenerative-associated transcriptional changes in the hippocampus of preterm fetal sheep independent of lung maturation

Upregulation of hepatic nuclear receptors in extremely preterm ovine fetuses undergoing artificial placenta therapy

A Reduction in Antenatal Steroid Dose Was Associated with Reduced Cardiac Dysfunction in a Sheep Model of Pregnancy

Respiratory benefit in preterm lambs is progressively lost when the concentration of fetal plasma betamethasone is titrated below two nanograms per milliliter

LPCAT1 levels in the placenta, the maternal plasma and the fetal plasma do not predict fetal lung responses to glucocorticoids in a sheep model of pregnancy

Pharmacological blockade of the interleukin-1 receptor suppressed Escherichia coli lipopolysaccharide-induced neuroinflammation in preterm fetal sheep

High Expression of Adrenal Cortisol Synthases Is Acquired After Intrauterine Inflammation in Periviable Sheep Fetuses

Artificial placenta support of extremely preterm ovine fetuses at the border of viability for up to 336 hours with maintenance of systemic circulation but reduced somatic and organ growth

Low-dose antenatal betamethasone treatment achieves preterm lung maturation equivalent to that of the World Health Organization dexamethasone regimen but with reduced endocrine disruption in a sheep model of pregnancy

Single nucleotide polymorphisms in surfactant protein A1 are not associated with a lack of responsiveness to antenatal steroid therapy in a pregnant sheep model

Continuous but not pulsed low-dose fetal betamethasone exposures extend the durability of antenatal steroid therapy

1% of the clinical dose used for antenatal steroid therapy is sufficient to induce lung maturation when administered directly to the preterm ovine fetus

The complex challenge of antenatal steroid therapy nonresponsiveness

Assessment of synthetic red cell therapy for extremely preterm ovine fetuses maintained on an artificial placenta life‐support platform

Perinatal care for the extremely preterm infant

Artificial placenta technology

Collaborators (7)

Zubair Amin

Tsukasa Takahashi

Yusaku Kumagai

Michael Clarke

Jeffrey Keelan

John P. Newnham

Lucy Furfaro

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