Helge Gad

University of Sheffield

United Kingdom

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Articles (7)

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Collaborators (8)

Evert Homan

Karolinska Institutet

SWEDEN

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Brinton Seashore-Ludlow

Karolinska Institutet

SWEDEN

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Therese M Pham

Karolinska Institutet

SWEDEN

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Mikael Altun

Karolinska Institutet

SWEDEN

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Bishoy Hanna

Karolinska Institutet

SWEDEN

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Sean Rudd

Assistant Professor

Karolinska Institutet

SWEDEN

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Päivi Östling

Karolinska Institutet

SWEDEN

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Julian Albers

Technical University of Munich

GERMANY

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Helge Gad

Research Interests

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Articles (7)

MTH1 inhibitor TH1579 induces oxidative DNA damage and mitotic arrest in acute myeloid leukemia

NEIL3 prevents senescence in hepatocellular carcinoma by repairing oxidative lesions at telomeres during mitosis

Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma

Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects

Targeting OGG1 arrests cancer cell proliferation by inducing replication stress

MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG

AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma

Collaborators (8)

Evert Homan

Brinton Seashore-Ludlow

Therese M Pham

Mikael Altun

Bishoy Hanna

Sean Rudd

Päivi Östling

Julian Albers

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