Sean Rudd

Assistant Professor

Karolinska Institutet

Sweden

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Articles (10)

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (11)

julie bianchi

Karolinska Institutet

SWEDEN

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Ann-Sofie Jemth

Karolinska Institutet

SWEDEN

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Thomas Helleday

Professor at Karolinska Institutet

Karolinska Institutet

SWEDEN

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Si Min Zhang

Karolinska Institutet

SWEDEN

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Evert Homan

Karolinska Institutet

SWEDEN

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Mikael Altun

Karolinska Institutet

SWEDEN

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Klas Wiman

Karolinska Institutet

SWEDEN

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Hanna Axelsson

Karolinska Institutet

SWEDEN

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Helge Gad

University of Sheffield

UNITED KINGDOM

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Vladimir Nakade Bykov

Karolinska Institutet

SWEDEN

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Nicholas Valerie

Karolinska Institutet

SWEDEN

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Sean Rudd

Research Interests

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Articles (10)

Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities.

Targeting the DNA damage response and repair in cancer through nucleotide metabolism.

The prognostic and clinicopathological significance of desmoglein 2 in human cancers: a systematic review and meta-analysis.

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity

NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.

A High-Throughput Enzyme-Coupled Activity Assay to Probe Small Molecule Interaction with the dNTPase SAMHD1.

Drug synergy scoring using minimal dose response matrices.

MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG

Development of a chemical probe against NUDT15

Collaborators (11)

julie bianchi

Ann-Sofie Jemth

Thomas Helleday

Si Min Zhang

Evert Homan

Mikael Altun

Klas Wiman

Hanna Axelsson

Helge Gad

Vladimir Nakade Bykov

Nicholas Valerie

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