Hiroaki WAKE

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教授/Professor

生理学研究所/National Institute for Physiological Sciences

Japan

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About

Hiroaki WAKE is a Professor at the National Institute for Physiological Sciences in Japan. His research focuses on various aspects of neurobiology and physiology, particularly the role of microglia in brain plasticity and the impact of environmental toxins on neural activity. Recent articles include studies on lipid droplets in liver diseases and advanced imaging techniques for evaluating neural function.

Recent Grants

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脳と免疫系相互作用の観点からの多階層的研究による精神疾患病態解明

Open Date: 2021-04-05

Close Date: 2024-03-31

Grant: Close

母体低栄養が新発見のGABA作動性CRH放出経路を介して仔の脳発達に与える影響

Open Date: 2021-04-01

Close Date: 2024-03-31

Grant: Close

ミクログリアによる感覚モダリティーの制御と精神病態への寄与

Open Date: 2021-04-01

Close Date: 2024-03-31

Grant: Close

Glia decoding: deciphering information critical for brain-body interactions

Open Date: 2020-11-19

Close Date: 2025-03-31

Grant: Close

全身臓器の生理的・病理的免疫状態遷移の脳による検出機構

Open Date: 2020-11-19

Close Date: 2025-03-31

Articles (10)

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2023

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2022

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2022

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2022

Collaborators (21)

Agnes NADJAR

Professor

University of Bordeaux

FRANCE

Hiroaki WAKE

Research Interests

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About

Recent Grants

Articles (10)

Distinct features of two lipid droplets types in cell nuclei from patients with liver diseases

Microglia enable cross-modal plasticity by removing inhibitory synapses

CD206+ macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia

Myelinated axon as a plastic cable regulating brain functions

Microglia states and nomenclature: A field at its crossroads

Elucidation of the neurological effects of clothianidin exposure at the no-observed-adverse-effect level (NOAEL) using two-photon microscopy in vivo imaging

A Piezo1/KLF15/IL-6 axis mediates immobilization-induced muscle atrophy.

Evaluation and Manipulation of Neural Activity using Two-Photon Holographic Microscopy

Lighting up cosmic neuronal networks with transformative in vivo calcium imaging

Ca<sup>2+</sup> imaging with two-photon microscopy to detect the disruption of brain function in mice administered neonicotinoid insecticides

Collaborators (21)

Agnes NADJAR

Yuki Hattori

Tetsushi Hirano

Rosa Chiara Paolicelli

Keisuke Oe

Harald Neumann

Dora Brites

Susanne Wolf

Amanda Sierra

Sonia GAREL

Melanie Greter

Valérie Wittamer

Hiroyuki Konishi

Francesca Peri

Bert Brône

Takaki Miyata

Pierre Gressens

Tuan Leng Tay

Ayano Kawaguchi

Takahiro Adachi

Yoshiaki Tabuchi

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