Amanda Sierra

Research Professor and Group Leader

Spain

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About

Amanda Sierra is a Research Professor and Group Leader at the Achucarro Basque Center for Neuroscience and the University of the Basque Country EHU/UPV in Spain. Her research focuses on microglial function, specifically in the context of myelin clearance, synaptic regulation, and phagocytosis in neurodegenerative diseases and brain injury. Recent publications highlight her contributions to understanding microglial activation, neuronal interactions, and the impact of dietary fatty acids on neurogenesis.

Articles (12)

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2025

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2025

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2025

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2024

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2023

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (22)

Jitao David Zhang

Assistent Lecturer

University of Basel

SWITZERLAND

Amanda Sierra

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Articles (12)

A bottom‐up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5

Microglia as hunters or gatherers of brain synapses

Interferons: Invited guests at the brain’s gala banquet

Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy

Microglia states and nomenclature: A field at its crossroads

Susceptibility of Female Mice to the Dietary Omega-3/Omega-6 Fatty-Acid Ratio: Effects on Adult Hippocampal Neurogenesis and Glia

Role of Mitochondrial Dynamics in Microglial Activation and Metabolic Switch

Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain

Microglial Corpse Clearance: Lessons From Macrophages.

Collaborators (22)

Jitao David Zhang

Agnes NADJAR

Rosa Chiara Paolicelli

Mirjana Maletic-Savatic

Harald Neumann

Hiroaki WAKE

Dora Brites

Susanne Wolf

Sonia GAREL

Aurore Thomazeau

Melanie Greter

GUILLERMO MARIÑO GARCÍA

Valérie Wittamer

Asier Ruiz

Bart J. L. Eggen

Francesca Peri

Bert Brône

Alejandro Carretero

Pierre Gressens

Jorge Valero

Tuan Leng Tay

Clémentine Bosch-Bouju

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