Hiroyuki Nakamura

Professor

Tokyo Institute of Technology

Japan

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About

Professor Hiroyuki Nakamura is a faculty member at the Tokyo Institute of Technology in Japan. His research encompasses various aspects of cancer therapy, notably boron neutron capture therapy and its applications in glioblastoma and head and neck squamous cell carcinoma models. Additionally, he investigates autophagy inhibitors and novel drug delivery systems, contributing to advancements in the field of photothermal agents and cancer treatment methodologies.

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2022

Collaborators (20)

Yuto Honda

Institute of Science Tokyo

JAPAN

Hiroyuki Nakamura

Research Interests

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About

Articles (26)

Comparative efficacy of reactor vs. accelerator-based boron neutron capture therapy in U87MG glioblastoma models

Boron neutron capture therapy with pteroyl-closo-dodecaborate-conjugated 4-(p-iodophenyl)butyric acid (PBC-IP) for a head and neck squamous cell carcinoma (SAS) model mice

Discovery of structurally diverse diazatricyclododecenes as lysosomotropic autophagy inhibitors

BODIPY-Based Photothermal Agent Incorporating Azulene for Enhanced NIR Absorption and Tumor Ablation

Magnetically Triggered Drug-Release System and Magnetic Caged Calcium Using Iron Oxide Nanoparticles and Hydrogels

Early Stage In Vitro Bioprofiling of Potential Low-Molecular-Weight Organoboron Compounds for Boron Neutron Capture Therapy (BNCT)—Proposal for a Guide

Development of carbonic anhydrase IX-targeting molecular-targeted photodynamic therapy

Zinc Carbenoid-Promoted Methylene Insertion in Saturated Heterocycles: Mechanistic Insights and Reactivity Profiles

Discovery of Disubstituted Carboranes as Inhibitors of Heat Shock Protein 90–Heat Shock Factor 1 Interaction

Methylene Insertion into Nitrogen‐Heteroatom Single Bonds of 1,2‐Azoles via a Zinc Carbenoid: An Alternative Tool for Skeletal Editing

Intracellular Photocatalytic Proximity Labeling (iPPL) for Dynamic Analysis of Chromatin-Binding Proteins Targeting Histone H3

Synthesis and Optimization of Ethylenediamine-Based Zwitterion on Polymer Side Chain for Recognizing Narrow Tumorous pH Windows

A Water-Soluble Small Molecule Boron Carrier Targeting Biotin Receptors for Neutron Capture Therapy

Discovery of sp3-rich diazatricycloundecanes as lysosomotropic autophagy inhibitors

Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated closo-Dodecaborate on a Rat Brain Tumor Model

Discovery of three-dimensional bicyclo[3.3.1]nonanols as novel heat shock protein 90 inhibitors

Asymmetric Synthesis of Bicyclic Isoxazolines via Dearomative Cycloaddition of 4-Nitroisoxazoles with Zwitterionic π-Allyl Palladium Species

Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts

Improved Boron Neutron Capture Therapy Using Integrin αvβ3-Targeted Long-Retention-Type Boron Carrier in a F98 Rat Glioma Model

Development of a Peptide Sensor Derived from Human ACE2 for Fluorescence Polarization Assays of the SARS-CoV-2 Receptor Binding Domain

Chemoselective α-Trifluoroacetylation of Amides Using Highly Electrophilic Trifluoroacetic Anhydrides and 2,4,6-Collidine

Development of a Gadolinium–Boron-Conjugated Albumin for MRI-Guided Neutron Capture Therapy

Cover Feature: Sequential Nucleophilic Substitution of Phosphorus Trichloride with Alcohols in a Continuous‐Flow Reactor and Consideration of a Mechanism for Reduced Over‐reaction through the Addition of Imidazole (Chem. Eur. J. 37/2022)

Sequential Nucleophilic Substitution of Phosphorus Trichloride with Alcohols in a Continuous‐Flow Reactor and Consideration of a Mechanism for Reduced Over‐reaction through the Addition of Imidazole

Photodynamic Therapy by Glucose Transporter 1-Selective Light Inactivation

Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-Functionalized <i>Closo</i>-Dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and <i>In Vivo</i> BNCT in the Hamster Cheek Pouch Oral Cancer Model

Collaborators (20)

Yuto Honda

Jun Takaya

Yoshinori Sakurai

Kohei Yoshimura

Yoshiki Fujikawa

Luigi PANZA

Eiji Matsuura

Shinichiro Fuse

Yutaka Miura

Minoru Suzuki

Hideki Kashiwagi

Naonori Hu

Agnieszka Boguslawa Olejniczak

Shinji Kawabata

Satoshi Okada

Takahiro Nomoto

Hideki Taguchi

Shinichi Sato

Kazuki Miura

Taiki Morita

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