Shinichiro Fuse

Professor

Nagoya University

Japan

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About

Shinichiro Fuse is a Professor at Nagoya University in Japan. His research focuses on microflow synthesis techniques, including the optimization of sequential coupling and cyclization processes, as well as the synthesis of various organic compounds. Recent publications highlight his work on the application of Bayesian optimization in synthesis and the development of methods to avoid undesired byproducts in peptide synthesis.

Articles (21)

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2025

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2024

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2023

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2022

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2022

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2022

Collaborators (4)

Shusaku Asano

Assistant Professor

Kyushu University

JAPAN

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Hiroyuki Nakamura

Professor

Tokyo Institute of Technology

JAPAN

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Naoto Yamasaki

Nagoya University

JAPAN

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Alexei Lapkin

University of Cambridge

UNITED KINGDOM

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Shinichiro Fuse

Research Interests

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About

Articles (21)

Optimizing microflow sequential coupling and cyclization of multiple linear substrates guided by Bayesian optimization

One-step syntheses of diaza-dioxa-fenestranes via the sequential (3 + 2) cycloadditions of linear precursors and their structural analyses

Effect of Brønsted Acids on the Activation of Mixed Anhydride/Mixed Carbonic Anhydride and C‐Terminal‐Free N‐Methylated Peptide Synthesis in a Micro‐Flow Reactor

Microflow, Sequential Coupling and Cyclization Approach for Synthesis of Cyclic Phosphotriesters from PCl3

Facile Generation of tert-Butoxycarbonyl Chloride Equivalent and Its Use in Microflow Reactor

Microflow Synthesis of Unsymmetrical H-Phosphonates via Sequential and Direct Substitution of Chlorine Atoms in Phosphorus Trichloride with Alkoxy Groups

Microflow Synthesis of Unsymmetrical <i>H</i>-Phosphonates via Sequential and Direct Substitution of Chlorine Atoms in Phosphorus Trichloride with Alkoxy Groups

One‐Flow Synthesis of Substituted Indoles via Sequential 1,2‐Addition/Nucleophilic Substitution of Indolyl‐3‐Carbaldehydes

Micro-flow heteroatom alkylation via TfOH-mediated rapid in situ generation of carbocations and subsequent nucleophile addition

Multi-objective Bayesian optimisation using q-noisy expected hypervolume improvement (qNEHVI) for the Schotten–Baumann reaction

Avoiding Undesired Intramolecular Diketopiperazine Formation during Peptoid Chain Elongation Using a Microflow Reactor

Switchable Synthesis of 7‐ and 14‐Membered Cyclic Peptides Containing N‐Methyl‐ and β‐Amino Acids Utilizing Microflow Technology

Peptide Cyclization by the Use of Acylammonium Species

Peptide Cyclization by the Use of Acylammonium Species

One-Flow Syntheses of Unsymmetrical Sulfamides and N-Substituted Sulfamate Esters

Continuous‐/Micro‐Flow Reactions Using Highly Electrophilic PCl3 and POCl3

Verification of preparations of (1H-indol-3-yl)methyl electrophiles and development of their microflow rapid generation and substitution

Rapid and column-chromatography-free peptide chain elongation via a one-flow, three-component coupling approach

Cover Feature: Sequential Nucleophilic Substitution of Phosphorus Trichloride with Alcohols in a Continuous‐Flow Reactor and Consideration of a Mechanism for Reduced Over‐reaction through the Addition of Imidazole (Chem. Eur. J. 37/2022)

Sequential Nucleophilic Substitution of Phosphorus Trichloride with Alcohols in a Continuous‐Flow Reactor and Consideration of a Mechanism for Reduced Over‐reaction through the Addition of Imidazole

Recent Advances in the Solid- and Solution-Phase Synthesis of Peptides and Proteins Using Microflow Technology

Collaborators (4)

Shusaku Asano

Hiroyuki Nakamura

Naoto Yamasaki

Alexei Lapkin

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