Hollis Showalter

Research Professor Emeritus of Medicinal Chemistry

University of Michigan

United States

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Hollis Showalter is a Research Professor Emeritus of Medicinal Chemistry at the University of Michigan, USA. His research primarily focuses on the optimization of benzoxazinorifamycins for the treatment of tuberculosis, as well as the synthesis of novel compounds targeting various diseases. Recent articles highlight his work on improving RNA polymerase inhibition and addressing co-infections related to HIV and tuberculosis.

Articles (5)

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Collaborators (2)

George A. Garcia

UNITED STATES

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Scott Franzblau

Professor and Director

University of Illinois Chicago (UIC)

UNITED STATES

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Hollis Showalter

Research Interests

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Articles (5)

Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis

Optimization of Benzoxazinorifamycins to Minimize hPXR Activation for the Treatment of Tuberculosis and HIV Coinfection

A novel synthesis of substituted 3‐amino and 3‐thio pyrimido[5,4‐e]‐1,2,4‐triazine‐5,7(1H,6H)‐diones

Synthesis of azide congeners of preQ1 as potential substrates for tRNA guanine transglycosylase

Recent Progress in the Discovery and Development of 2-Nitroimidazooxazines and 6-Nitroimidazooxazoles to Treat Tuberculosis and Neglected Tropical Diseases

Collaborators (2)

George A. Garcia

Scott Franzblau

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