Hooman Soleymani majd
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Articles (11)
Year:
2023
Year:
2023
Mixed endometrial carcinoma (MEEC) refers to rare endometrial tumours that are composed of two or more distinct histotypes, at least one of which is serous or clear cell. The aim of this study was to evaluate the epidemiology, treatment outcomes and survival rates of patients with mixed endometrial carcinoma. The medical records of 34 patients diagnosed with MEEC between March 2010 and January 2020 were reviewed retrospectively. Clinicopathological variables and treatment strategies were assessed, and overall survival and disease-free survival rates were evaluated. The histology of endometrioid and serous component was found in 26 (76.5%) patients, followed by serous and clear-cell components (5/34, 14.5%) and mixed endometrioid serous and clear-cell components (3/34, 8.8%). The median age at diagnosis was 70 years (range 52–84), and the median follow-up time was 55 months. The 5-year disease-free survival and the 5-year overall survival were 50.4% and 52.4%, respectively. Advanced disease stage was identified as an independent predictor of inferior disease-free (<0.003) and overall survival (p < 0.001). Except for stage, none of the traditional prognostic factors was associated with disease recurrence or death from disease. MEECs represent rare high-risk endometrial carcinomas with significant diagnostic and treatment challenges. Undoubtedly, the implementation of a molecular analysis can offer further diagnostic and management insights.
Year:
2023
Year:
2023
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2023
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2023
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2023
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2023
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2023
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2023
Year:
2023
Collaborators (50)
James Glasbey
University of Birmingham
Munenori Kusunoki
Kansai Medical University
Dickon Hayne
University of Western Australia
Janet Martin
Associate Professor
Western University
Andreas Älgå
Associate Professor of Surgery
Karolinska Institutet Institutionen för klinisk forskning och utbildning Södersjukhuset
YAMINI SUBRAMANI
Western University
Jaiganesh Manickavasagam
Honorary, Honorary Senior Lecturer
University of Dundee
Shaikh Sanjid Seraj
Associate Lecturer
Anglia Ruskin University
Jasper Stijns
Vrije Universiteit Brussel
Franco ODICINO
Professore Ordinario
University of Brescia
Francesk Mulita
University Hospital of Patras
Maria Picciochi
University of Birmingham
Alfredo Annicchiarico
University of Parma
Mirko Barone
-
Shafaque Shaikh
Honorary Senior Clinical Lecturer
University of Aberdeen
Wiktor Krawczyk
Medical University of Silesia
Susana Gonzalez Suarez
Universitat Autònoma de Barcelona (UAB)
Ahmad Ozair
Johns Hopkins University Bloomberg School of Public Health
Francesco Colombo
-
Gianluca Franceschini
Professore associato Universitario, per il settore scientifico-disciplinare MED/18 Chirurgia Generale
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tarik Sammour
Associate Professor
Royal Adelaide Hospital
Nicola Colucci
Cambridge University Hospitals
Ryckie Wade
NIHR Academic Clinical Lecturer
-
sara Tamburello
University of Florence
Georg Singer
Resident, Assistant Professor, Consultant, Associate Professor
Medical University of Graz
Patrick A Coughlin
Cambridge University Hospitals NHS Foundation Trust
Antonio Simone Laganà
Assistant Professor (Researcher type B) in Obstetrics and Gynecology
Università degli Studi di Palermo
anastasios kanatas
Professor
-
Jugpal Arneja
Clinical Professor
The University of British Columbia
Marc Vallve-Bernal
Associate Professor
Universitat Rovira i Virgili
Mahesh Nagappa
Associate Professor
Western University
George Garas
Consultant ENT / Head & Neck Surgeon (Surgical Oncology)
University Hospitals Birmingham NHS Foundation Trust
Gerardo Perrotta
Vita-Salute San Raffaele University
Dmitri Nepogodiev
NIHR Academic Clinical Lecturer in Surgical Epidemiology & Public Health
University of Birmingham
Tom Abbott
NIHR Clinical Lecturer
Queen Mary University of London
Kai Yuen Wong
Cambridge University Hospitals NHS Foundation Trust
Luis Joaquín García Flórez
Head, Coloproctology Section
Central University Hospital of Asturias
JAVIER MATA
Head of Department
La Paz University Hospital
Alessia D’Amico
Psycho-Neurobiology master - Qualified lecturer
Sapienza University of Rome
Hugo Layard Horsfall
Imperial College London
GIAN MARCO PRUCHER
Consultant Oral, Maxillofacial, Head and Neck Surgeon
Azienda Ospedaliero-Universitaria Maggiore della Carità
Florian Recker
University Hospital Bonn
Neil Sharma
Consultant Head and Neck Surgeon
Queen Elizabeth Hospital Birmingham
Ramesh M Nataraja
-
Julio Domenech Fernández
Head of Department
Clinica Universidad de Navarra
Arne Böttcher
-
Gerardo Petruzzi
Istituto Regina Elena
Alexis R. Narvaez‐Rojas
-
marcello migliore
Full Professor Thoracic Surgery
University of Catania
Tural Alekberli
Assistant Professor, Staff Anesthesiologist
Dalhousie University
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