Jasper Stijns

Vrije Universiteit Brussel

Belgium

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Articles (25)

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2025

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2025

Aim Anal fistula is one of the most common anal diseases, affecting between 1 and 3 per 10 000 people per year. Symptoms have a potentially severe effect on a patient's quality of life. Surgery is the mainstay of treatment, aiming to cure the fistula and preserve anal sphincter function. Rectal advancement flap (RAF) is currently the gold standard treatment but has recurrence rates varying between 20% and 50% and might lead to disturbance of continence. The aim of the trial described in this work is to discover if the minimally invasive fistula tract laser closure (FiLaC™) technique could achieve higher healing rates and a better functional outcome than RAF. Method We will perform a randomized prospective multicentre noninferiority study of the treatment of high trans‐sphincteric perianal fistulas, comparing FiLaC™ with RAF in terms of fistula healing, recurrence rate, functional outcome and quality of life. Primary and secondary fistula healing will be evaluated at 26 and 52 weeks’ follow‐up. Quality of life will be evaluated using the SF‐36 questionnaire, the Faecal Incontinence Quality of Life Scale questionnaire and the Vaizey score at 3, 6, 12 and 26 weeks postoperatively. Conclusion High trans‐sphincteric fistulas have a potentially severe effect on a patient's quality of life. Classical treatment with RAF is a time‐consuming invasive procedure. The LATFIA trial aims to compare FiLaC™ with the gold standard treatment with RAF. In case of noninferiority, FiLaC™ treatment could be standardized as a first line treatment for high trans‐sphincteric fistulas. Better conservation of the patient's anal sphincter function could possibly be obtained. Likewise, we will report on the postoperative quality of life when applying these two techniques.

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (229)

Marian Vanhoeij

Vrije Universiteit Brussel

BELGIUM

Jasper Stijns

Research Interests

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Articles (25)

Ventral mesh rectopexy

Routine Preoperative CT Scanning of Patients with Anorectal Sepsis is not Useful. A Retrospective Cohort Study

Protocol of the <scp>LATFIA</scp> trial (Laser Assisted Treatment of Fistula in Ano): a multicentre, prospective, randomized controlled trial comparing fistula‐tract laser closure (<scp>FiLaC™</scp>) with rectal advancement flap for high trans‐sphincteric fistulas

Quality of Reporting on Anastomotic Leaks in Colorectal Cancer Trials: A Systematic Review

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries.

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.

Association between multimorbidity and postoperative mortality in patients undergoing major surgery: a prospective study in 29 countries across Europe

Impact of postoperative cardiovascular complications on 30-day mortality after major abdominal surgery: an international prospective cohort study.

Burnout among surgeons before and during the SARS-CoV-2 pandemic

Distalization of perianal fistulas after loose silicone seton drainage is a myth

Validation of a 3D-printed model of cryptoglandular perianal fistulas

Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study

Belgian consensus guideline on the management of anal fissures.

Global treatment of haemorrhoids—A worldwide snapshot audit conducted by the International Society of University Colon and Rectal Surgeons

Anastomotic leak after manual circular stapled left-sided bowel surgery: analysis of technology-, disease-, and patient-related factors.

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries.

Intestinal ischemia in COVID-19 patients : a case series

Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.

Safe implementation of robotic right colectomy with intracorporeal anastomosis

Anal fistula, there is more than meets the eye!

SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study

An international assessment of the adoption of enhanced recovery after surgery (ERAS®) principles across colorectal units in 2019–2020

BJS commission on surgery and perioperative care post-COVID-19

Are novel knot-free setons also trouble-free?

ESCP Safe Anastomosis ProGramme in CoLorectal SurgEry (EAGLE): Study protocol for an international cluster randomised trial of a quality improvement intervention to reduce anastomotic leak following right colectomy

Collaborators (229)

Marian Vanhoeij

Vaihere Delaune

James Glasbey

Mina Youssef

HERMAN SEHMBI

Munenori Kusunoki

IOANNIS VALIOULIS

Jacobo Trebol

Ladislao Cayetano Paniagua

Dickon Hayne

Chikashi Takeda

Enoch Akowuah

Matteo Marro

Daniel Perez

Najia Azhar

Hiroshi Yonekura

Janet Martin

Paola Calleja Hermosa

Andreas Älgå

Federico Ghignone

Laura Sala

Michael Farrell

Julius Orhalmi

David A Clark

michele maria carvello

Thomas Curl-Roper

ludi smeele

Marion Delpont

YAMINI SUBRAMANI

Pierpaolo Sileri

BALTASAR PÉREZ-SABORIDO

Ruth Christine Schäfer

Luca Bruschini

Erik Agger

Saam Tourani

Ahmed Elshabrawy

Nolan Bruce

Daniel Jacobs-Tulleneers-Thevissen

Jiali Gao

Jaiganesh Manickavasagam

Rachel Shu-En Lau

Ulrich Ronellenfitsch

Shaikh Sanjid Seraj

Paola Zinser Peniche

Marisa Domingues Santos

David Bosanquet

Alastair Morton

Fanourios Georgiades

Paolo MERCANTINI