Ikumi Tamai

Kanazawa University

Japan

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Articles (11)

The specific effect of apples on constipation is due to the reduced expression of ASBT, which increases intestinal luminal BAs, thereby promoting the motility of the gut and the water content, resulting in the relief of constipation.

Year:

2023

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (3)

Hisakazu Komori

Assistant Professor

Kanazawa University

JAPAN

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Thanigaimalai Pillaiyar

Eberhard Karls Universität Tübingen

GERMANY

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Sho Konno

Tokyo University of Pharmacy and Life Sciences

JAPAN

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Ikumi Tamai

Research Interests

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Articles (11)

Apple juice relieves loperamide-induced constipation in rats by downregulating the intestinal apical sodium-dependent bile acid transporter ASBT

Apple-derived extracellular vesicles modulate the expression of human intestinal bile acid transporter ASBT/SLC10A2 via downregulation of transcription factor RARα

Potentiation of the Uricosuric Effect of Dotinurad byTrans-Inhibition of the Uric Acid Reabsorptive Transporter URAT1

Induction of open-form bile canaliculus formation by hepatocytes for evaluation of biliary drug excretion

Apple juice relieves loperamide-induced constipation in rats by downregulating the intestinal apical sodium-dependent bile acid transporter ASBT

Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening

3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents

MicroRNAs in apple-derived nanoparticles modulate intestinal expression of OATP2B1/SLCO2B1 in Caco-2 cells

Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo

CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages

Identification of Triterpene Acids in Poria cocos Extract as Bile Acid Uptake Transporter Inhibitors

Collaborators (3)

Hisakazu Komori

Thanigaimalai Pillaiyar

Sho Konno

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