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Sho Konno

Tokyo University of Pharmacy and Life Sciences

Japan

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Research Interests

Biochemistry

80%

Biochemical Engineering

40%

Peptide Chemistry

50%

Chemical Biology

50%

Protein Chemistry

50%

Enzyme Engineering

30%

Bioanalytical Chemistry

30%

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Articles19

Tryptophan‐Selective Chemical Modification of Peptides by Thioether‐Mediated Sulfenylation

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Year:

2025

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions

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Year:

2025

Exploring the Substrate Flexibility of GrsB Thioesterase Leads to the Structural Reassignment of a Gramicidin S Variant

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Year:

2025

Inhibition of Surfactin Biosynthesis in Bacillus Subtilis Using Cell‐Permeable Adenylation Domain Inhibitors

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Year:

2025

Probing for optimal photoaffinity linkers of benzophenone-based photoaffinity probes for adenylating enzymes

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Year:

2024

Detection of Active SARS-CoV-2 3CL Protease in Infected Cells Using Activity-Based Probes with a 2,6-Dichlorobenzoyloxymethyl Ketone Reactive Warhead

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Year:

2024

Development of a chemical scaffold for inhibiting nonribosomal peptide synthetases in live bacterial cells

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Year:

2024

Backbone resonance assignments of the C-terminal thioesterase domain of tyrocidine synthetase C

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Year:

2024

Peptide mixed phosphonates for covalent complex formation with thioesterases in nonribosomal peptide synthetases

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Year:

2023

Development of Conformationally Restricted Negamycin Derivatives for Potent Readthrough Activity

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Year:

2023

Establishment of One-Pot Disulfide-Driven Cyclic Peptide Synthesis with a 3-Nitro-2-pyridinesulfenate

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Year:

2023

Exploring a chemical scaffold for rapid and selective photoaffinity labelling of non-ribosomal peptide synthetases in living bacterial cells

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Year:

2023

Inactivation of myostatin by photooxygenation using functionalized <scp>d</scp>-peptides

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Year:

2023

Chemoproteomics profiling of surfactin-producing nonribosomal peptide synthetases in living bacterial cells

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Year:

2022

Chemical Synthesis of an HIV-1 Protease Analog with Some Amides in a Polypeptide Main Chain Replaced by Disulfide Bonds

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Year:

2022

3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents

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Year:

2021

Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation

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Year:

2021

Inhibition of efflux pumps aids small-molecule probe-based fluorescence labeling and imaging in the Gram-negative bacterium: Escherichia coli

Article Link

Year:

2021

Structural Revision of Natural Cyclic Depsipeptide MA026 Established by Total Synthesis and Biosynthetic Gene Cluster Analysis

Article Link

Year:

2021

Collaborators8

Keisuke Hamada

Tokyo University of Pharmacy and Life Sciences

JAPAN

Ikumi Tamai

Kanazawa University

JAPAN

Yoshio Hayashi

Tokyo University of Pharmacy and Life Sciences

JAPAN

Hideaki Kakeya

Professor

Kyoto University

JAPAN

Yuuta Fujikawa

Associate Professor

Tokyo University of Pharmacy and Life Sciences

JAPAN

Kentaro Takayama

Kyoto Pharmaceutical University

JAPAN

Thanigaimalai Pillaiyar

Eberhard Karls Universität Tübingen

GERMANY

Atsuhiko Taniguchi

Tokyo University of Pharmacy and Life Sciences

JAPAN

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