Irene Papatheodorou

Head of Data Science

Earlham Institute

United Kingdom

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Dr. Irene Papatheodorou is the Head of Data Science at the Earlham Institute in the UK. Her research focuses on areas such as single-cell transcriptomics, multi-omics analysis, and the application of gene ontology in understanding cellular functions across species. Recently, she has contributed to studies on cell-type deconvolution, cancer evolution, and the impacts of environmental factors on non-model organisms.

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

Collaborators (5)

David Osumi-Sutherland

Wellcome Sanger Institute

UNITED KINGDOM

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Pedro Madrigal

EMBL-European Bioinformatics Institute

UNITED KINGDOM

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Montserrat Climent

Assistant Professor in Biochemistry

Humanitas University

ITALY

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Norbert Perrimon

Adjunct Professor, FlyBase PI

Harvard University

UNITED STATES

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Andrew Jones

Professor

University of Liverpool

UNITED KINGDOM

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Irene Papatheodorou

Research Interests

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Articles (10)

ScGOclust: leveraging gene ontology to find functionally analogous cell types between distant species

Genetic and Pharmacological Inhibition of Metabotropic Glutamate Receptor Signalling Extends Lifespan in Drosophila.

Integrated Proteomics Analysis of Baseline Protein Expression in Pig Tissues.

Alleviating batch effects in cell type deconvolution with SCCAF-D

Building a FAIR data ecosystem for incorporating single-cell transcriptomics data into agricultural genome to phenome research.

Single-cell RNA sequencing offers opportunities to explore the depth of physiology, adaptation, and biochemistry in non-model organisms exposed to pollution.

Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution

CATD: a reproducible pipeline for selecting cell-type deconvolution methods across tissues

Expression Atlas update: insights from sequencing data at both bulk and single cell level

Canonical Wnt and TGF-β/BMP signaling enhance melanocyte regeneration but suppress invasiveness, migration, and proliferation of melanoma cells.

Collaborators (5)

David Osumi-Sutherland

Pedro Madrigal

Montserrat Climent

Norbert Perrimon

Andrew Jones

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