Irina Portier

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Washington University in St. Louis

United States

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Recent Grants

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Platelet Mammalian Target of Rapamycin regulates ischemic stroke brain injury

Open Date: 2022-01-01

Close Date: 2023-12-31

Articles (10)

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2025

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

Collaborators (4)

Frederik Denorme

Assistant Professor

Washington University in St. Louis

UNITED STATES

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Marvin Nieman

Professor

Case Western Reserve University School of Medicine

UNITED STATES

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Christian Yost

Professor - Neonatology

University of Utah

UNITED STATES

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Ramesh Grandhi

University of Utah

UNITED STATES

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Irina Portier

Research Interests

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Recent Grants

Articles (10)

Mitochondrial Calcium Uniporter Regulates ITAM-Dependent Platelet Activation

Aging-related alterations in mechanistic target of rapamycin signaling promote platelet hyperreactivity and thrombosis.

Platelets, plasma, and proteostasis: a translation tightrope.

Finding a fountain of youth in the blood

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

Actin-bundling protein L-plastin promotes megakaryocyte rigidity and dampens proplatelet formation.

Neutrophil extracellular trap inhibition improves survival in neonatal mouse infectious peritonitis.

Neutrophil extracellular traps regulate ischemic stroke brain injury

MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis

Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5.

Collaborators (4)

Frederik Denorme

Marvin Nieman

Christian Yost

Ramesh Grandhi

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