Isabelle Taylor

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Assistant Professor

William & Mary

United States

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Recent Grants

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Targeting the bacterialthioesterase, PqsE, for the treatment of Pseudomonas aeruginosa infections

Open Date: 2019-09-01

Close Date: 2022-08-31

Articles (8)

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (3)

Bonnie L. Bassler

Princeton University

UNITED STATES

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Philip Jeffrey

Princeton University

UNITED STATES

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Sue-Ann Mok

Assistant Professor

University of Alberta

CANADA

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Isabelle Taylor

Research Interests

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Contact this professor

Recent Grants

Articles (8)

The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against <i>Pseudomonas aeruginosa</i>.

Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa

Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer

The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in Pseudomonas aeruginosa

Inhibitor Mimetic Mutations in the <i>Pseudomonas aeruginosa</i> PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.

Functional genomics screen identifies proteostasis targets that modulate prion protein (PrP) stability.

Discovery of PqsE Thioesterase Inhibitors for Pseudomonas aeruginosa Using DNA-Encoded Small Molecule Library Screening

Tryptophan scanning mutagenesis as a way to mimic the compound-bound state and probe the selectivity of allosteric inhibitors in cells

Collaborators (3)

Bonnie L. Bassler

Philip Jeffrey

Sue-Ann Mok

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