J. Mark Sutton

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Professor for Antimicrobial Therapy

King's College London - Waterloo Campus

United Kingdom

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About

J. Mark Sutton is a Professor for Antimicrobial Therapy at King's College London - Waterloo Campus. His research focuses on antimicrobial resistance, the efficacy of biocides, and novel therapeutic strategies, as evidenced by his recent publications on the mechanisms of bacterial tolerance and the development of antimicrobial peptides. His work includes significant studies on the tolerance of clinical isolates to various cationic biocides and the use of ultrasound-responsive microbubbles in treating biofilms.

Recent Grants

Grant: Close

Cleaning validation for surgical instrument reprocessing

Open Date: 2010-04-01

Close Date: 2012-03-31

Grant: Close

Evaluation of Ozone Sterilisation as Methods for Inactivation of TSE Agents

Open Date: 2005-04-01

Close Date: 2009-01-31

Articles (12)

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2025

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2023

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2022

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2022

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2022

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2021

Collaborators (12)

Hywel Morgan

Professor of Bioelectronics

University of Southampton

UNITED KINGDOM

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Sandra Wilks

Associate Professor

University of Southampton

UNITED KINGDOM

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Senior Lecturer in Molecular Biology

University of the West of England

UNITED KINGDOM

View details

Dario Carugo

Lecturer

University College London

UNITED KINGDOM

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J. Mark Sutton

Research Interests

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About

Recent Grants

Articles (12)

Prevalence of mutations associated with tolerance to chlorhexidine and other cationic biocides among Proteus mirabilis clinical isolates

QSAR Reveals Decreased Lipophilicity of Polar Residues Determines the Selectivity of Antimicrobial Peptide Activity

Electrical Broth Micro-Dilution for Rapid Antibiotic Resistance Testing

Genomic Diversity of Bacteriophages Infecting the Genus Acinetobacter

Temporin B forms hetero-oligomers with Temporin L, modifies its membrane activity and increases the cooperativity of its antibacterial pharmacodynamic profile

Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms

Efflux-mediated tolerance to cationic biocides, a cause for concern?

Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of 'druggable' supramolecular self-associating antimicrobial amphiphiles.

Bactericidal Effect of Ultrasound-Responsive Microbubbles and Sub-inhibitory Gentamicin against Pseudomonas aeruginosa Biofilms on Substrates With Differing Acoustic Impedance.

Mutations in SilS and CusS/OmpC represent different routes to achieve high level silver ion tolerance in Klebsiella pneumoniae.

Contribution of the efflux pump AcrAB-TolC to the tolerance of chlorhexidine and other biocides in <i>Klebsiella</i> spp.

Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling.

Collaborators (12)

Hywel Morgan

Sandra Wilks

Jose L. Ortega-Roldan

Peter Glynne-Jones

Emma Denham

Hugo Oliveira

Benjamin Evans

James Mason

Christian Lorenz

Roland Fleck

Dann Turner

Dario Carugo

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